Reproductive aging is characterized by a decline in oocyte quantity and quality, which is
directly associated with a decline in reproductive potential, as well as poorer reproductive …

The mitogen-activated protein kinase (MAPK) cascade is one of the most important of the
intracellular signaling pathways that play a crucial role in cell proliferation, cell differentiation …

Chromatin configuration in the germinal vesicle (GV) undergoes dynamic changes during
oocyte growth, yet little is known about the mechanisms regulating chromatin remodeling in …

Homologous gap junctions are generally recognized as a means of coordinating cellular
behavior under developmental and homeostatic conditions. In the mammalian ovary …

Mitogen-activated protein kinase (MAPK) is a family of Ser/Thr protein kinases that are
widely distributed in eukaryotic cells. Studies in the last decade revealed that MAPK …

This study tested the hypothesis that murine oocytes participate in the establishment of
granulosa cell phenotypic heterogeneity in preovulatory follicles. In these follicles, mural …

This paper is a review of the current status of technology for mammalian oocyte growth and
development in vitro. It compares and contrasts the characteristics of the various culture …

This study investigated the participation of MAPK in the resumption of meiosis [germinal
vesicle breakdown (GVB)] in oocytes and cumulus expansion using oocyte-cumulus cell …

Reviews in Developmental Biology have covered the pathways that generate the all-
important intracellular calcium (Ca2+) signal at fertilization [Miyazaki, S., Shirakawa, H …

The molecular basis for acquisition of meiotic and developmental competence, the two main
outcomes of oocyte development and essential for producing an egg capable of being …