SS Chang, Z Zhang, Y Liu - Annual review of microbiology, 2012 - annualreviews.org
RNA interference (RNAi) is a conserved eukaryotic gene regulatory mechanism that uses small noncoding RNAs to mediate posttranscriptional/transcriptional gene silencing. The …
Eukaryotes have evolved complex mechanisms to repair DNA double-strand breaks (DSBs) through coordinated actions of protein sensors, transducers, and effectors. Here we show …
The error-free and efficient repair of DNA double-stranded breaks (DSBs) is extremely important for cell survival. RNA has been implicated in the resolution of DNA damage but the …
Y Dang, Q Yang, Z Xue, Y Liu - Eukaryotic cell, 2011 - Am Soc Microbiol
Small RNA molecules of about 20 to 30 nucleotides function in gene regulation and genomic defense via conserved eukaryotic RNA interference (RNAi)-related pathways. The …
PA Dumesic, P Natarajan, C Chen, IA Drinnenberg… - Cell, 2013 - cell.com
Using the yeast Cryptococcus neoformans, we describe a mechanism by which transposons are initially targeted for RNAi-mediated genome defense. We show that intron-containing …
R Aramayo, EU Selker - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
The filamentous fungus Neurospora crassa has provided a rich source of knowledge on epigenetic phenomena that would have been difficult or impossible to gain from other …
KM Michalik, R Böttcher, K Förstemann - Nucleic acids research, 2012 - academic.oup.com
Small RNAs have been implicated in numerous cellular processes, including effects on chromatin structure and the repression of transposons. We describe the generation of a …
S Torres-Martínez… - Annual Review of …, 2017 - annualreviews.org
RNA interference (RNAi) is a conserved eukaryotic mechanism that uses small RNA molecules to suppress gene expression through sequence-specific messenger RNA …
T Gall-Duncan, J Luo, CM Jurkovic, LA Fischer, K Fujita… - Cell, 2023 - cell.com
Expansions of repeat DNA tracts cause> 70 diseases, and ongoing expansions in brains exacerbate disease. During expansion mutations, single-stranded DNAs (ssDNAs) form …