Drug-induced liver injury (DILI) is a problem of increasing significance, but has been a long-
standing concern in the treatment of tuberculosis (TB) infection. The liver has a central role …

The cornerstone of tuberculosis management is a 6‐month course of isoniazid, rifampicin,
pyrazinamide and ethambutol. Compliance is crucial for curing tuberculosis. Adverse effects …

Naphthalene, a cytotoxic moiety, is an extensively explored aromatic conjugated system with
applications in various pathophysiological conditions viz. anticancer, antimicrobial, anti …

The aim of this review is to present the current state of knowledge on human latent
tuberculosis infection (LTBI) based on clinical studies and observations, as well as …

Introduction: Tuberculosis continues to be a major cause of morbidity and mortality
worldwide. Currently available drugs are effective for treatment of the disease or latent …

In view of the increased risk of TB reactivation with anti-TNF alpha treatment, various
professional groups have sought the advice of the Joint Tuberculosis Committee of the …

BACKGROUND: There is renewed attention to the critical role of successfully treating latent
tuberculosis infection (LTBI) in reducing the overall impact of tuberculosis (TB). However …

Rationale: We examined whether increased rifampin doses could shorten standard therapy
for tuberculosis without increased toxicity. Objectives: To assess the differences across three …

Isoniazid is an efficacious treatment for latent tuberculosis. Concerns remain, however,
regarding hepatotoxicity associated with this medication. In addition, adherence may be …

OBJECTIVE: Side effects of the most commonly used primary antituberculosis (anti-TB)
drugs may be mild as well as fatal. The aim of this study was to evaluate the side effects of …