A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …

This review gives an overview of the protective role of CD8+ T cells in SARS-CoV-2
infection. The cross-reactive responses intermediated by CD8+ T cells in unexposed cohorts …

The emergence of SARS-CoV-2 variants of concern (VOC) is driven by mutations that
mediate escape from neutralizing antibodies. There is also evidence that mutations can …

The novel mRNA-based vaccines against SARS-CoV-2 display encouraging safety and
efficacy profiles. However, there is a paucity of data regarding their immunogenicity and …

Patients with hematological malignancies are prioritized for COVID-19 vaccine due to their
high risk for severe SARS-CoV-2 infection-related disease and mortality. To understand T …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection remains in a
global pandemic, and no eradicative therapy is currently available. Host T cells have been …

CD8+ T cell immunity, mediated by human leukocyte antigen (HLA) and T cell receptor
(TCR), plays a critical role in conferring immune memory and protection against viral …

ABSTRACT T cell immunity is crucial for long-term immunological memory, but the profile of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific memory T cells in …

T-cell immunity, mediated by CD4+ and CD8+ T cells, represents a cornerstone in the
control of viral infections. Virus-derived T-cell epitopes are represented by human leukocyte …

Omicron BA. 1 variant can readily infect people with vaccine-induced or naturally acquired
SARS-CoV-2 immunity facilitated by escape from neutralizing antibodies. In contrast, T-cell …