Human CD56bright NK cells: an update

T Michel, A Poli, A Cuapio, B Briquemont… - The Journal of …, 2016 - journals.aai.org
Human NK cells can be subdivided into various subsets based on the relative expression of
CD16 and CD56. In particular, CD56 bright CD16−/dim NK cells are the focus of interest …

Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

H Hegen, J Walde, K Berek… - Multiple Sclerosis …, 2023 - journals.sagepub.com
Background: Intrathecal immunoglobulin-G synthesis is a hallmark of multiple sclerosis
(MS), which can be detected by oligoclonal IgG bands (OCB) or by κ-free light chains (κ …

Monitoring disease activity in multiple sclerosis using serum neurofilament light protein

L Novakova, H Zetterberg, P Sundström, M Axelsson… - Neurology, 2017 - AAN Enterprises
Objective: To examine the effects of disease activity, disability, and disease-modifying
therapies (DMTs) on serum neurofilament light (NFL) and the correlation between NFL …

Seizures after ischemic stroke: a matched multicenter study

C Ferreira‐Atuesta, N Döhler… - Annals of …, 2021 - Wiley Online Library
Objective The purpose of this study was to identify risk factors for acute symptomatic
seizures and post‐stroke epilepsy after acute ischemic stroke and evaluate the effects of …

Proinflammatory and anti-inflammatory cytokines in the CSF of patients with Alzheimer's disease and their correlation with cognitive decline

R Taipa, SP das Neves, AL Sousa, J Fernandes… - Neurobiology of …, 2019 - Elsevier
Cumulative data suggest that neuroinflammation plays a prominent role in Alzheimer's
disease (AD) pathogenesis. The purpose of this work was to assess if patients with AD …

GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis

E Galli, FJ Hartmann, B Schreiner, F Ingelfinger… - Nature medicine, 2019 - nature.com
Cytokine dysregulation is a central driver of chronic inflammatory diseases such as multiple
sclerosis (MS). Here, we sought to determine the characteristic cellular and cytokine …

Body fluid biomarkers in multiple sclerosis

M Comabella, X Montalban - The Lancet Neurology, 2014 - thelancet.com
Biomarkers can be thought of as multifaceted indicators of healthy status or of pathological
disorders. The study of multiple sclerosis can benefit from the use of biomarkers because of …

Age‐and disease‐specific reference values for neurofilament light presented in an online interactive support interface

L Vermunt, M Otte, IMW Verberk… - Annals of Clinical …, 2022 - Wiley Online Library
Abstract Interpretation of axonal damage biomarker Neurofilament Light chain (NfL)
concentrations is difficult due to the lack of age‐specific and disease‐specific reference …

Circulating miRNAs as potential biomarkers in Alzheimer's disease

D Galimberti, C Villa, C Fenoglio… - Journal of …, 2014 - content.iospress.com
Several micro (mi) RNA are deregulated in brain, cerebrospinal fluid (CSF), and
serum/plasma from patients with Alzheimer's disease (AD). The aim of the study was to …

Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes

E Canto, M Tintore, LM Villar, C Costa, R Nurtdinov… - Brain, 2015 - academic.oup.com
Abstract Chitinase 3-like 1 (CHI3L1) has been proposed as a biomarker associated with the
conversion to clinically definite multiple sclerosis in patients with clinically isolated …