Utility of repeated praziquantel dosing in the treatment of schistosomiasis in high-risk communities in Africa: a systematic review

CH King, SK Olbrych, M Soon, ME Singer… - PLoS neglected …, 2011 - journals.plos.org
Background Controversy persists about the optimal approach to drug-based control of
schistosomiasis in high-risk communities. In a systematic review of published studies, we …

Natural products as a source for treating neglected parasitic diseases

D Ndjonka, LN Rapado, AM Silber, E Liebau… - International Journal of …, 2013 - mdpi.com
Infectious diseases caused by parasites are a major threat for the entire mankind, especially
in the tropics. More than 1 billion people world-wide are directly exposed to tropical …

Efficacy and safety of praziquantel 40 mg/kg in preschool-aged and school-aged children: a meta-analysis

J Zwang, P Olliaro - Parasites & vectors, 2017 - Springer
Background Children carry most of the schistosomiasis burden. While school-aged children
are the principal target group of preventive chemotherapy with praziquantel, limited …

History of schistosomiasis epidemiology, current status, and challenges in China: on the road to schistosomiasis elimination

LG Song, XY Wu, M Sacko, ZD Wu - Parasitology research, 2016 - Springer
Schistosomiasis is a snail-borne disease caused by worms of the genus Schistosoma.
Worldwide, human schistosomiasis remains a serious public health problem, threatening∼ …

Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental …

G Zdesenko, F Mutapi - PLoS neglected tropical diseases, 2020 - journals.plos.org
Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as
preventive chemotherapy as part of national helminth control strategies. Given the heavy …

Artemether and praziquantel: origin, mode of action, impact, and suggested application for effective control of human schistosomiasis

R Bergquist, H Elmorshedy - Tropical medicine and infectious disease, 2018 - mdpi.com
The stumbling block for the continued, single-drug use of praziquantel (PZQ) against
schistosomiasis is less justified by the risk of drug resistance than by the fact that this drug is …

Efficacy of praziquantel and reinfection patterns in single and mixed infection foci for intestinal and urogenital schistosomiasis in Cameroon

LAT Tchuenté, SC Momo, JR Stothard, D Rollinson - Acta tropica, 2013 - Elsevier
The regular administration of the anthelminthic drug praziquantel (PZQ) to school-aged
children (and other high-risk groups) is the cornerstone of schistosomiasis control. Whilst the …

[HTML][HTML] Novel therapeutic and prevention approaches for schistosomiasis

RAF El Ridi, HAM Tallima - Journal of Advanced Research, 2013 - Elsevier
Schistosomiasis is a debilitating disease affecting approximately 600 million people in 74
developing countries, with 800 million, mostly children at risk. To circumvent the threat of …

Prevalence and Reinfection Rates of Schistosoma mansoni and Praziquantel Efficacy against the Parasite among Primary School Children in Sanja Town, Northwest …

E Woldegerima, AG Bayih, Y Tegegne… - Journal of …, 2019 - Wiley Online Library
Background. Schistosomiasis is among the most widespread chronic infections in the world.
The magnitude of the infection may show variations across different areas with respect to …

Schistosomiasis in Egypt: A never-ending story?

AA Othman, RH Soliman - Acta tropica, 2015 - Elsevier
Schistosomiasis has plagued the Egyptian population since the antiquity. The disease is still
a public health problem in Egypt, despite the tendency of being overlooked. In the first part of …