Irreversible protein aggregation is problematic in the biotechnology industry, where
aggregation is encountered throughout the lifetime of a therapeutic protein, including during …

Because understanding amyloid fibrillation in molecular detail is essential for development
of strategies to control amyloid formation and overcome neurodegenerative disorders …

Amyloid β-peptide (Aβ), the pathogenic agent of Alzheimer disease, is a physiological
metabolite whose levels are constantly controlled in normal brain. Recent studies have …

Bacillus subtilis forms biofilms whose constituent cells are held together by an extracellular
matrix. Previous studies have shown that the protein TasA and an exopolysaccharide are …

In the search for the molecular mechanism of insulin fibrillation, the kinetics of insulin fibril
formation were studied under different conditions using the fluorescent dye thioflavin T …

Inhibition of the accumulation of amyloid β‐peptide (Aβ) and the formation of β‐amyloid
fibrils (fAβ) from Aβ, as well as the destabilization of preformed fAβ in the central nervous …

Protein aggregation is an important phenomenon that alternatively is part of the normal
functioning of nature or, central to this review, has negative consequences via its …

Abstract Cerebral deposition of amyloid β-peptide (Aβ) in the brain is an invariant feature of
Alzheimer's disease (AD). A consistent protective effect of wine consumption on AD has …

Amyloid fibrils and amorphous aggregates are two types of aberrant aggregates associated
with protein misfolding diseases. Although they differ in morphology, the two forms are often …

Polyphosphate (polyP) consists of a linear arrangement of inorganic phosphates and defies
its structural simplicity with an astounding number of different activities in the cell. Already …