[HTML][HTML] Latest views on the mechanisms of action of surgically implanted cervical vagal nerve stimulation in epilepsy

R Carron, P Roncon, S Lagarde, M Dibué… - … : Technology at the …, 2023 - Elsevier
Background Vagus nerve stimulation (VNS) is approved as an adjunctive treatment for drug-
resistant epilepsy. Although there is a substantial amount of literature aiming at unraveling …

Bioelectronic medicine for the autonomic nervous system: clinical applications and perspectives

M Cracchiolo, MM Ottaviani, A Panarese… - Journal of Neural …, 2021 - iopscience.iop.org
Bioelectronic medicine (BM) is an emerging new approach for developing novel
neuromodulation therapies for pathologies that have been previously treated with …

[HTML][HTML] Quantitative estimation of nerve fiber engagement by vagus nerve stimulation using physiological markers

YC Chang, M Cracchiolo, U Ahmed, I Mughrabi… - Brain stimulation, 2020 - Elsevier
Background Cervical vagus nerve stimulation (VNS) is a rapidly emerging bioelectronic
treatment for brain, metabolic, cardiovascular and immune disorders. Its desired and off …

Closed-loop vagus nerve stimulation for the treatment of cardiovascular diseases: state of the art and future directions

MM Ottaviani, F Vallone, S Micera… - Frontiers in …, 2022 - frontiersin.org
The autonomic nervous system exerts a fine beat-to-beat regulation of cardiovascular
functions and is consequently involved in the onset and progression of many cardiovascular …

[HTML][HTML] Vagus nerve stimulation elicits sleep EEG desynchronization and network changes in responder patients in epilepsy

S Vespa, J Heyse, L Stumpp, G Liberati, SF Santos… - …, 2021 - Elsevier
Neural desynchronization was shown as a key mechanism of vagus nerve stimulation (VNS)
action in epilepsy, and EEG synchronization measures are explored as possible response …

Using neural biomarkers to personalize dosing of vagus nerve stimulation

A Berthon, L Wernisch, M Stoukidi, M Thornton… - Bioelectronic …, 2024 - Springer
Background Vagus nerve stimulation (VNS) is an established therapy for treating a variety of
chronic diseases, such as epilepsy, depression, obesity, and for stroke rehabilitation …

Validated computational models predict vagus nerve stimulation thresholds in preclinical animals and humans

ED Musselman, NA Pelot, WM Grill - Journal of Neural …, 2023 - iopscience.iop.org
Objective. We demonstrated how automated simulations to characterize electrical nerve
thresholds, a recently published open-source software for modeling stimulation of peripheral …

Laterality, sexual dimorphism, and human vagal projectome heterogeneity shape neuromodulation to vagus nerve stimulation

NP Biscola, PM Bartmeyer, Y Beshay, E Stern… - Communications …, 2024 - nature.com
Neuromodulation by vagus nerve stimulation (VNS) provides therapeutic benefits in multiple
medical conditions, including epilepsy and clinical depression, but underlying mechanisms …

Transcutaneous cervical vagus nerve magnetic stimulation in patients with traumatic brain injury: a feasibility study

H Zhang, Y Zhao, Y Qu, J Du, Y Peng - Neuromodulation: Technology at …, 2024 - Elsevier
Objectives Transcutaneous vagus nerve stimulation has shown promising results in
improving cognitive and motor function after stroke. However, to our knowledge, there have …

Laryngeal muscle-evoked potential recording as an indicator of vagal nerve fiber activation

C Bouckaert, R Raedt, LE Larsen, R El Tahry… - … : Technology at the …, 2022 - Elsevier
Background Vagus nerve stimulation (VNS) is an adjunctive therapy for drug-resistant
epilepsy. Noninvasive evoked potential recordings in laryngeal muscles (LMEPs) innervated …