Towards a unified open access dataset of molecular interactions
Abstract The International Molecular Exchange (IMEx) Consortium provides scientists with a
single body of experimentally verified protein interactions curated in rich contextual detail to …
single body of experimentally verified protein interactions curated in rich contextual detail to …
The IntAct database: efficient access to fine-grained molecular interaction data
N Del Toro, A Shrivastava, E Ragueneau… - Nucleic acids …, 2022 - academic.oup.com
The IntAct molecular interaction database (https://www. ebi. ac. uk/intact) is a curated
resource of molecular interactions, derived from the scientific literature and from direct data …
resource of molecular interactions, derived from the scientific literature and from direct data …
Using biological networks to integrate, visualize and analyze genomics data
Network biology is a rapidly developing area of biomedical research and reflects the current
view that complex phenotypes, such as disease susceptibility, are not the result of single …
view that complex phenotypes, such as disease susceptibility, are not the result of single …
DeepViral: prediction of novel virus–host interactions from protein sequences and infectious disease phenotypes
Motivation Infectious diseases caused by novel viruses have become a major public health
concern. Rapid identification of virus–host interactions can reveal mechanistic insights into …
concern. Rapid identification of virus–host interactions can reveal mechanistic insights into …
HitPredict version 4: comprehensive reliability scoring of physical protein–protein interactions from more than 100 species
HitPredict is a consolidated resource of experimentally identified, physical protein–protein
interactions with confidence scores to indicate their reliability. The study of genes and their …
interactions with confidence scores to indicate their reliability. The study of genes and their …
Hepatic dysfunction caused by consumption of a high-fat diet
Obesity is a major human health crisis that promotes insulin resistance and, ultimately, type
2 diabetes. The molecular mechanisms that mediate this response occur across many highly …
2 diabetes. The molecular mechanisms that mediate this response occur across many highly …
HENA, heterogeneous network-based data set for Alzheimer's disease
Alzheimer's disease and other types of dementia are the top cause for disabilities in later life
and various types of experiments have been performed to understand the underlying …
and various types of experiments have been performed to understand the underlying …
Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics
The COVID-19 disease is an ongoing global health concern. Although vaccination provides
some protection, people are still susceptible to re-infection. Ostensibly, certain populations …
some protection, people are still susceptible to re-infection. Ostensibly, certain populations …
IntAct App: a Cytoscape application for molecular interaction network visualization and analysis
E Ragueneau, A Shrivastava, JH Morris… - …, 2021 - academic.oup.com
Abstract Summary IntAct App is a Cytoscape 3 application that grants in-depth access to
IntAct's molecular interaction data. It build networks where nodes are interacting molecules …
IntAct's molecular interaction data. It build networks where nodes are interacting molecules …
Current status and future perspectives of computational studies on human–virus protein–protein interactions
X Lian, X Yang, S Yang, Z Zhang - Briefings in Bioinformatics, 2021 - academic.oup.com
The protein–protein interactions (PPIs) between human and viruses mediate viral infection
and host immunity processes. Therefore, the study of human–virus PPIs can help us …
and host immunity processes. Therefore, the study of human–virus PPIs can help us …