The stringent response and physiological roles of (pp) pGpp in bacteria
SE Irving, NR Choudhury, RM Corrigan - Nature Reviews Microbiology, 2021 - nature.com
The stringent response is a stress signalling system mediated by the alarmones guanosine
tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp) in response to nutrient …
tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp) in response to nutrient …
Recent functional insights into the role of (p) ppGpp in bacterial physiology
The alarmones guanosine tetraphosphate and guanosine pentaphosphate (collectively
referred to as (p) ppGpp) are involved in regulating growth and several different stress …
referred to as (p) ppGpp) are involved in regulating growth and several different stress …
Insights into the phylogeny and coding potential of microbial dark matter
Genome sequencing enhances our understanding of the biological world by providing
blueprints for the evolutionary and functional diversity that shapes the biosphere. However …
blueprints for the evolutionary and functional diversity that shapes the biosphere. However …
Transcriptional responses to ppGpp and DksA
RL Gourse, AY Chen, S Gopalkrishnan… - Annual review of …, 2018 - annualreviews.org
The stringent response to nutrient deprivation is a stress response found throughout the
bacterial domain of life. Although first described in proteobacteria for matching ribosome …
bacterial domain of life. Although first described in proteobacteria for matching ribosome …
MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis
Critical to the bacterial stringent response is the rapid relocation of resources from
proliferation toward stress survival through the respective accumulation and degradation of …
proliferation toward stress survival through the respective accumulation and degradation of …
The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life
GC Atkinson, T Tenson, V Hauryliuk - PloS one, 2011 - journals.plos.org
RelA/SpoT Homologue (RSH) proteins, named for their sequence similarity to the RelA and
SpoT enzymes of Escherichia coli, comprise a superfamily of enzymes that synthesize …
SpoT enzymes of Escherichia coli, comprise a superfamily of enzymes that synthesize …
ppGpp: magic beyond RNA polymerase
ZD Dalebroux, MS Swanson - Nature Reviews Microbiology, 2012 - nature.com
During stress, bacteria undergo extensive physiological transformations, many of which are
coordinated by ppGpp. Although ppGpp is best known for enhancing cellular resilience by …
coordinated by ppGpp. Although ppGpp is best known for enhancing cellular resilience by …
Regulatory themes and variations by the stress-signaling nucleotide alarmones (p) ppGpp in bacteria
Bacterial stress-signaling alarmones are important components of a protective network
against diverse stresses such as nutrient starvation and antibiotic assault. pppGpp and …
against diverse stresses such as nutrient starvation and antibiotic assault. pppGpp and …
[HTML][HTML] Direct regulation of GTP homeostasis by (p) ppGpp: a critical component of viability and stress resistance
Cells constantly adjust their metabolism in response to environmental conditions, yet major
mechanisms underlying survival remain poorly understood. We discover a …
mechanisms underlying survival remain poorly understood. We discover a …
Anion recognition and sensing with Zn (II)–dipicolylamine complexes
HT Ngo, X Liu, KA Jolliffe - Chemical Society Reviews, 2012 - pubs.rsc.org
Anion recognition and sensing with Zn( ii )–dipicolylamine complexes - Chemical Society
Reviews (RSC Publishing) DOI:10.1039/C2CS35087D Royal Society of Chemistry View PDF …
Reviews (RSC Publishing) DOI:10.1039/C2CS35087D Royal Society of Chemistry View PDF …