[HTML][HTML] Gender-specific effects of pro-longevity interventions in Drosophila

O Lushchak, O Strilbytska, KB Storey - Mechanisms of ageing and …, 2023 - Elsevier
Sex differences in lifespan are well recognized in the majority of animal species. For
example, in male versus female Drosophila melanogaster there are significant differences in …

[HTML][HTML] A gut-derived hormone suppresses sugar appetite and regulates food choice in Drosophila

A Malita, O Kubrak, T Koyama, N Ahrentløv… - Nature …, 2022 - nature.com
Animals must adapt their dietary choices to meet their nutritional needs. How these needs
are detected and translated into nutrient-specific appetites that drive food-choice behaviours …

[HTML][HTML] Amplification is the primary mode of gene-by-sex interaction in complex human traits

C Zhu, MJ Ming, JM Cole, MD Edge, M Kirkpatrick… - Cell Genomics, 2023 - cell.com
Sex differences in complex traits are suspected to be in part due to widespread gene-by-sex
interactions (GxSex), but empirical evidence has been elusive. Here, we infer the mixture of …

Energy as the cornerstone of environmentally driven sex allocation

B Geffroy - Trends in Endocrinology & Metabolism, 2022 - cell.com
In recent years, observations of distinct organisms have linked the quality of the environment
experienced by a given individual and the sex it will develop. In most described cases …

[HTML][HTML] The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress

O Kubrak, T Koyama, N Ahrentløv, L Jensen… - Nature …, 2022 - nature.com
The intestine is a central regulator of metabolic homeostasis. Dietary inputs are absorbed
through the gut, which senses their nutritional value and relays hormonal information to …

[HTML][HTML] Drosophila melanogaster as a Model Organism for Obesity and Type-2 Diabetes Mellitus by Applying High-Sugar and High-Fat Diets

N Baenas, AE Wagner - Biomolecules, 2022 - mdpi.com
Several studies have been published introducing Drosophila melanogaster as a research
model to investigate the effects of high-calorie diets on metabolic dysfunctions. However …

Ion transport peptide regulates energy intake, expenditure, and metabolic homeostasis in Drosophila

M Gáliková, P Klepsatel - Genetics, 2022 - academic.oup.com
In mammals, energy homeostasis is regulated by the antagonistic action of hormones insulin
and glucagon. However, in contrast to the highly conserved insulin, glucagon is absent in …

Spenito-dependent metabolic sexual dimorphism intrinsic to fat storage cells

AV Diaz, D Stephenson, T Nemkov, A D'Alessandro… - Genetics, 2023 - academic.oup.com
Metabolism in males and females is distinct. Differences are usually linked to sexual
reproduction, with circulating signals (eg hormones) playing major roles. In contrast, sex …

[HTML][HTML] Cellular sex throughout the organism underlies somatic sexual differentiation

C Hérault, T Pihl, B Hudry - Nature Communications, 2024 - nature.com
Sex chromosomes underlie the development of male or female sex organs across species.
While systemic signals derived from sex organs prominently contribute to sex-linked …

Characteristics of serum lipid levels in patients with hypertension: a hospital-based retrospective descriptive study

H Wu, Z Yu, Q Huang - BMJ open, 2022 - bmjopen.bmj.com
Background Dyslipidaemia is different among patients with hypertension in different
populations. The serum lipid profiles among Hakka patients with hypertension in southern …