Quantitative approaches to guide epilepsy surgery from intracranial EEG

JM Bernabei, A Li, AY Revell, RJ Smith… - Brain, 2023 - academic.oup.com
Over the past 10 years, the drive to improve outcomes from epilepsy surgery has stimulated
widespread interest in methods to quantitatively guide epilepsy surgery from intracranial …

Emerging roles of network analysis for epilepsy

W Stacey, M Kramer, K Gunnarsdottir… - Epilepsy research, 2020 - Elsevier
In recent years there has been increasing interest in applying network science tools to EEG
data. At the 2018 American Epilepsy Society conference in New Orleans, LA, the yearly …

Neural fragility as an EEG marker of the seizure onset zone

A Li, C Huynh, Z Fitzgerald, I Cajigas, D Brusko… - Nature …, 2021 - nature.com
Over 15 million patients with epilepsy worldwide do not respond to drugs. Successful
surgical treatment requires complete removal or disconnection of the seizure onset zone …

Source-sink connectivity: A novel interictal EEG marker for seizure localization

KM Gunnarsdottir, A Li, RJ Smith, JY Kang… - Brain, 2022 - academic.oup.com
Over 15 million epilepsy patients worldwide have drug-resistant epilepsy. Successful
surgery is a standard of care treatment but can only be achieved through complete resection …

Stimulation to probe, excite, and inhibit the epileptic brain

B Frauscher, F Bartolomei, MO Baud, RJ Smith… - …, 2023 - Wiley Online Library
Direct cortical stimulation has been applied in epilepsy for nearly a century and has
experienced a renaissance, given unprecedented opportunities to probe, excite, and inhibit …

Diagnosing epilepsy with normal interictal EEG using dynamic network models

P Myers, KM Gunnarsdottir, A Li… - Annals of …, 2023 - Wiley Online Library
Objective Whereas a scalp electroencephalogram (EEG) is important for diagnosing
epilepsy, a single routine EEG is limited in its diagnostic value. Only a small percentage of …

Neural fragility of the intracranial EEG network decreases after surgical resection of the epileptogenic zone

A Li, P Myers, N Warsi, KM Gunnarsdottir, S Kim… - medRxiv, 2021 - medrxiv.org
Over 15 million patients with epilepsy worldwide do not respond to medical therapy and may
benefit from surgical treatment. In cases of focal epilepsy, surgical treatment requires …

Virtual stimulation of the interictal EEG network localizes the EZ as a measure of cortical excitability

SR Zhai, SV Sarma, K Gunnarsdottir… - Frontiers in Network …, 2024 - frontiersin.org
Introduction: For patients with drug-resistant epilepsy, successful localization and surgical
treatment of the epileptogenic zone (EZ) can bring seizure freedom. However, surgical …

Sources and sinks in interictal iEEG networks: An iEEG marker of the epileptogenic zone

KM Gunnarsdottir, J Gonzalez-Martinez… - 2021 43rd Annual …, 2021 - ieeexplore.ieee.org
Around 30% of epilepsy patients have seizures that cannot be controlled with medication.
The most effective treatments for medically resistant epilepsy are interventions that surgically …

Estimating intracranial EEG signals at missing electrodes in epileptic networks

KM Gunnarsdottir, J Bulacio… - 2019 41st Annual …, 2019 - ieeexplore.ieee.org
Epilepsy can be controlled by targeted treatment of the epileptogenic zone (EZ), the region
in the brain where seizures originate. Identification of the EZ often requires visual inspection …