Diabetic retinopathy (DR), a sight-threatening neurovasculopathy, is the leading cause of
irreversible blindness in the developed world. DR arises as the result of prolonged …

Chronic kidney disease (CKD) is an aging-related disorder that represents a major global
public health burden. Current biochemical biomarkers, such as serum creatinine and urinary …

In the present study, we applied iTRAQ-based quantitative approach to explore the salivary
proteome and peptidome profile in selected subjects with type 1 diabetes, with and without …

New magnetic nanoprobes based on surface-functionalized magnetite particles were
synthesized and used to selectively capture metalloproteases from human saliva samples …

Diabetic kidney disease (DKD) affects an estimated 20–40% of type 2 diabetes patients and
is among the most prevalent microvascular complications in this patient population …

A growing body of evidence suggests a role of proteolytic enzymes in the development of
diabetic nephropathy. Cathepsin C (CatC) is a well-known regulator of inflammatory …

Chronic kidney disease (CKD) is the gradual decrease in renal function. Currently available
biomarkers are effective only in detecting late stage CKD. Biomarkers of early stage CKD …

Sodium, although essential for life, is a key factor in changes in vascular function and
cardiovascular disease when consumed in excess. Sarcocornia spp., a halophyte plant with …

Background Lower urinary tract symptoms (LUTS) and prostate specific antigen-based
parameters seem to have only a limited utility for the differential diagnosis of prostate cancer …

Background Chronic progression of diabetes is associated with decreased pancreatic islet
mass due to apoptosis of β-cells. Patients with diabetes have increased circulating matrix …