Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …

Antibodies, particularly of the immunoglobulin G (IgG) isotype, are a group of biomolecules
that are extensively used as affinity reagents for many applications in research, disease …

Immune checkpoint inhibitor (ICI) therapy has emerged as a major treatment option for a
variety of cancers. Among the immune checkpoints addressed, the programmed death …

Simple Summary Malignant cells hijack the regulatory roles of immune checkpoint proteins
for immune evasion and survival. Therapeutics blocking those proteins can restore the …

Immunotherapy is an effective therapeutic option for several cancers. In the last years, the
introduction of checkpoint inhibitors (ICIs) has shifted the therapeutic landscape in oncology …

Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) checkpoint blockade is a major
breakthrough in cancer therapy, but identifying patients likely to benefit from this therapy …

Despite advances in immunotherapy for the treatment of cancers, not all patients can benefit
from programmed cell death ligand 1 (PD-L1) immune checkpoint blockade therapy. Anti-PD …

Novel targeted therapies are rapidly emerging for the treatment of cancer. With the advent of
new immune targeting agents, understanding the changes in the tumor microenvironment …

Therapies that modulate immune response to cancer, such as immune checkpoint inhibitors,
began an intense development a few years ago; however, in breast cancer (BC), the results …