Hyperphosphatemia is a predictable consequence of chronic renal failure and is present in
most patients on dialysis. Traditionally, the risk associated with elevated serum phosphorus …

A summary of new findings regarding alterations of magnesium (Mg 2+) and phosphorus (P)
metabolism are reviewed for the clinician caring for patients in general wards. Alterations in …

Disturbances in mineral and bone metabolism are common in patients with CKD. A large
body of evidence indicates that these derangements are associated with increased mortality …

Calcium, phosphorus, and magnesium homeostasis is altered in chronic kidney disease
(CKD). Hypocalcemia, hyperphosphatemia, and hypermagnesemia are not seen until …

Dietary phosphorus (P) restriction is known to ameliorate secondary hyperparathyroidism in
renal failure patients. In early renal failure, this effect may be mediated by an increase in 1 …

Secondary hyperparathyroidism is characterized by an increase in parathyroid (PT) cell
number, and parathyroid hormone (PTH) synthesis and secretion. It is still unknown as to …

Cardiovascular disease (CVD) is highly prevalent in the setting of chronic kidney disease
(CKD). Such coexistence of CVD and CKD—the so-called “cardiorenal or renocardiac …

Bone loss and increased fractures are common complications in chronic kidney disease.
Because Wnt pathway activation is essential for normal bone mineralization, we assessed …

Pathogenesis of secondary hyperparathyroidism. Secondary hyperparathyroidism is a
universal complication in patients with chronic renal failure. Hyperplasia of the parathyroid …

Phosphorus retention is an important factor in the development of hyperparathyroidism
secondary to renal failure. In vivo manipulation of phosphorus is associated with changes in …