A review and database of snake venom proteomes

T Tasoulis, GK Isbister - Toxins, 2017 - mdpi.com
Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in …

[HTML][HTML] Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

B Lomonte, JJ Calvete - Journal of Venomous Animals and Toxins …, 2017 - SciELO Brasil
This work offers a general overview on the evolving strategies for the proteomic analysis of
snake venoms, and discusses how these may be combined through diverse experimental …

Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead

JM Gutiérrez, G Solano, D Pla, M Herrera, Á Segura… - Toxins, 2017 - mdpi.com
Animal-derived antivenoms constitute the mainstay in the therapy of snakebite envenoming.
The efficacy of antivenoms to neutralize toxicity of medically-relevant snake venoms has to …

Snake venomics: from the inventory of toxins to biology

JJ Calvete - Toxicon, 2013 - Elsevier
A deep understanding of the composition of venoms and of the principles governing the
evolution of venomous systems is of applied importance for exploring the enormous …

Next-generation snake venomics: protein-locus resolution through venom proteome decomplexation

JJ Calvete - Expert review of proteomics, 2014 - Taylor & Francis
Venom research has been continuously enhanced by technological advances. High-
throughput technologies are changing the classical paradigm of hypothesis-driven research …

Cobra venom proteome and glycome determined from individual snakes of Naja atra reveal medically important dynamic range and systematic geographic variation

HW Huang, BS Liu, KY Chien, LC Chiang… - Journal of …, 2015 - Elsevier
Recent progress in snake venomics has shed much light on the intra-species variation
among the toxins from different geographical regions and has provided important …

Venomics of New World pit vipers: genus-wide comparisons of venom proteomes across Agkistrodon

B Lomonte, WC Tsai, JM Ureña-Diaz, L Sanz… - Journal of …, 2014 - Elsevier
We report a genus-wide comparison of venom proteome variation across New World pit
vipers in the genus Agkistrodon. Despite the wide variety of habitats occupied by this genus …

A comparative study of venomics of Naja naja from India and Sri Lanka, clinical manifestations and antivenomics of an Indian polyspecific antivenom

K Sintiprungrat, K Watcharatanyatip… - Journal of …, 2016 - Elsevier
Naja naja (Indian cobra) from Sri Lanka and India is the WHO Category 1 medically
important snakes in both countries. Some antivenom produced against Indian N. naja (NNi) …

Proteomic characterization and comparison of venoms from two elapid snakes (Bungarus multicinctus and Naja atra) from China

LL Shan, JF Gao, YX Zhang, SS Shen, Y He, J Wang… - Journal of …, 2016 - Elsevier
Bungarus multicinctus (many-banded krait) and Naja atra (Chinese cobra) are widely
distributed and medically important venomous snakes in China; however, their venom …

Immunological profile of antivenoms: Preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays

JM Gutiérrez, B Lomonte, L Sanz, JJ Calvete, D Pla - Journal of proteomics, 2014 - Elsevier
Parenteral administration of animal-derived antivenoms constitutes the mainstay in the
treatment of snakebite envenomings. Despite the fact that this therapy has been available for …