Drugs and targets in fibrosis

X Li, L Zhu, B Wang, M Yuan, R Zhu - Frontiers in pharmacology, 2017 - frontiersin.org
Fibrosis contributes to the development of many diseases and many target molecules are
involved in fibrosis. Currently, the majority of fibrosis treatment strategies are limited to …

Protein and peptide delivery to lungs by using advanced targeted drug delivery

DK Chellappan, P Prasher, V Saravanan… - Chemico-biological …, 2022 - Elsevier
The challenges and difficulties associated with conventional drug delivery systems have led
to the emergence of novel, advanced targeted drug delivery systems. Therapeutic drug …

Regulation of airway smooth muscle contraction in health and disease

M Lam, E Lamanna, JE Bourke - Smooth muscle spontaneous activity …, 2019 - Springer
Airway smooth muscle (ASM) extends from the trachea throughout the bronchial tree to the
terminal bronchioles. In utero, spontaneous phasic contraction of fetal ASM is critical for …

Emerging pharmaceutical therapies for COPD

SP Lakshmi, AT Reddy, RC Reddy - International journal of chronic …, 2017 - Taylor & Francis
COPD, for which cigarette smoking is the major risk factor, remains a worldwide burden.
Current therapies provide only limited short-term benefit and fail to halt progression. A …

Emerging therapeutic modalities against COVID-19

S Malik, A Gupta, X Zhong, TP Rasmussen… - Pharmaceuticals, 2020 - mdpi.com
The novel SARS-CoV-2 virus has quickly spread worldwide, bringing the whole world as
well as the economy to a standstill. As the world is struggling to minimize the transmission of …

Neuroendocrine cells derived chemokine vasoactive intestinal polypeptide (VIP) in allergic diseases

AK Verma, M Manohar, SU Venkateshaiah… - Cytokine & growth factor …, 2017 - Elsevier
Worldwide increase incidences of allergic diseases have heightened the interest of
clinicians and researchers to understand the role of neuroendocrine cells in the recruitment …

The molecular blueprint for chronic obstructive pulmonary disease (COPD): a new paradigm for diagnosis and therapeutics

I Shakeel, A Ashraf, M Afzal, SS Sohal… - Oxidative Medicine …, 2023 - Wiley Online Library
The global prevalence of chronic obstructive pulmonary disease (COPD) has increased over
the last decade and has emerged as the third leading cause of death worldwide. It is …

Emerging biologics for the treatment of pulmonary arterial hypertension

T Hye, MR Hossain, D Saha, T Foyez… - Journal of Drug …, 2023 - Taylor & Francis
Pulmonary arterial hypertension (PAH) is a rare pulmonary vascular disorder, wherein mean
systemic arterial pressure (mPAP) becomes abnormally high because of aberrant changes …

Vasoactive intestinal peptide, whose receptor‐mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse

M Bertolini, M Pretzlaff, M Sulk, M Bähr… - British Journal of …, 2016 - academic.oup.com
Background Alopecia areata (AA) is an autoimmune disorder whose pathogenesis involves
the collapse of the relative immune privilege (IP) of the hair follicle (HF). Given that …

[HTML][HTML] Vasoactive intestinal peptide promotes corneal allograft survival

V Satitpitakul, Z Sun, K Suri, A Amouzegar… - The American Journal of …, 2018 - Elsevier
Corneal transplantation is the most prevalent form of tissue transplantation. The success of
corneal transplantation mainly relies on the integrity of corneal endothelial cells (CEnCs) …