Proteotoxic stress, that is, stress caused by protein misfolding and aggregation, triggers the
rapid and global reprogramming of transcription at genes and enhancers. Genome-wide …

The ubiquitin-related SUMO system controls many cellular signaling networks. In
mammalian cells, three SUMO forms (SUMO1, SUMO2 and SUMO3) act as covalent …

One major role of the eukaryotic peptidic post-translational modifier SUMO in the cell is
transcriptional control. This occurs via modification of virtually all classes of transcriptional …

Plants encounter several abiotic stresses, among which heat stress is gaining paramount
attention because of the changing climatic conditions. Severe heat stress conspicuously …

Sumoylation is the covalent attachment of the small ubiquitin-related modifier (SUMO) to a
vast variety of proteins in order to modulate their function. Sumoylation has emerged as an …

SUMOylation is a post-translational modification that has emerged in recent decades as a
mechanism involved in controlling diverse physiological processes and that is essential in …

With the increasing global warming, high-temperature stress is affecting plant growth and
development with greater frequency. Therefore, an increasing number of studies examining …

Proteotoxic stress such as heat shock causes heat-shock factor (HSF)-dependent
transcriptional upregulation of chaperones. Heat shock also leads to a rapid and reversible …

Highlights•SUMOylation controls the protein-protein interactions, subcellular localization,
and stability of transcription factors.•SUMOylation contributes to transcriptional regulation …

Conjugation with the small ubiquitin-like modifier (SUMO) constitutes a key post-
translational modification regulating the stability, activity, and subcellular localization of its …