The application of patient-derived organoid in the research of lung cancer
Lung cancer is the most common cancer and the leading cause of cancer-related death
worldwide. However, mechanisms of its progression remained unclear and new treatments …
worldwide. However, mechanisms of its progression remained unclear and new treatments …
Molecular insights of metastasis and cancer progression derived using 3D cancer spheroid co-culture in vitro platform
The multistep metastasis process is carried out by the combinatorial effect of the stromal
cells and the cancerous cells and plays vital role in the cancer progression. The …
cells and the cancerous cells and plays vital role in the cancer progression. The …
Advanced lung organoids and lung-on-a-chip for cancer research and drug evaluation: a review
L Zhu, J Zhang, Q Guo, J Kuang, D Li, M Wu… - … in Bioengineering and …, 2023 - frontiersin.org
Lung cancer has become the primary cause of cancer-related deaths because of its high
recurrence rate, ability to metastasise easily, and propensity to develop drug resistance. The …
recurrence rate, ability to metastasise easily, and propensity to develop drug resistance. The …
Acute cytotoxicity test of PM2. 5, NNK and BPDE in human normal bronchial epithelial cells: A comparison of a co-culture model containing macrophages and a mono …
J Zhou, H Zou, Y Liu, Y Chen, Y Du, J Liu, Z Huang… - Toxicology in Vitro, 2022 - Elsevier
Background Based on extensive research on cytotoxicity of exogenous compounds in vitro,
it is essential to develop a cell model that better mimics environment in vivo to explore …
it is essential to develop a cell model that better mimics environment in vivo to explore …
[HTML][HTML] Navigating the Complexity of Resistance in Lung Cancer Therapy: Mechanisms, Organoid Models, and Strategies for Overcoming Treatment Failure
Background: The persistence of chemotherapy-resistant and dormant cancer cells remains a
critical challenge in the treatment of lung cancer. Objectives: This review focuses on non …
critical challenge in the treatment of lung cancer. Objectives: This review focuses on non …
Two-dimensional and three-dimensional cell culture and their applications
S Ballav, AJ Deshmukh, S Siddiqui… - … and Applications in …, 2021 - books.google.com
Cell culture is one of the most important and commonly used in vitro tools to comprehend
various aspects of cells or tissues of a living body such as cell biology, tissue morphology …
various aspects of cells or tissues of a living body such as cell biology, tissue morphology …
Changes in stem cell regulation and epithelial organisation during carcinogenesis and disease progression in gynaecological malignancies
P Cunnea, C Fotopoulou, J Ploski, F Trillsch, S Mahner… - Cancers, 2021 - mdpi.com
Simple Summary Recent advances in our understanding of the stem cell potential in adult
tissues have far-reaching implications for cancer research, and this creates new …
tissues have far-reaching implications for cancer research, and this creates new …
How Far Are We from Research That Is Independent of the Use of Animal Models? A Comparative Analysis between Animal and 3D/On-a-Chip Models for the Study of …
S Burgio, OM Manna, G Intili, F Cappello… - Applied …, 2023 - mdpi.com
Over the last ten years, with the progress of in vitro culture methods, it has been possible to
build increasingly reliable models to effectively mimic in vivo ones. The translational …
build increasingly reliable models to effectively mimic in vivo ones. The translational …
[HTML][HTML] An investigation to identify tumor microenvironment-related genes of prognostic value in lung squamous cell carcinoma based on The Cancer Genome Atlas
H Liu, B Liu, L Zhang, M Li, C Chen, S He… - Translational Cancer …, 2021 - ncbi.nlm.nih.gov
Background Lung squamous cell carcinoma (LUSC) is a prevalent and lethal malignancy
with a poor clinical prognosis. Major constituents of the tumor microenvironment (TME) …
with a poor clinical prognosis. Major constituents of the tumor microenvironment (TME) …