The keratins are the typical intermediate filament proteins of epithelia, showing an
outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing …

A great hallmark of breast cancer is the absence or presence of estrogen receptors ERα and
ERβ, with a dominant role in cell proliferation, differentiation and cancer progression. Both …

Abstract Background Cytokeratin 18 (CK18) is an intermediate filament protein of the
cytokeratin acidic type I group and is primarily expressed in single-layered or “simple” …

In spite of the vast amount of research and the advances, oral squamous cell carcinoma
implies quite significant mortality and morbidity rates. This has motivated the search of …

Abstract Background Targeting the c-Met signaling pathway has become a therapeutic
strategy in multiple types of cancer. We unveiled a novel c-Met regulating mechanism that …

Abstract Purpose: Cytokeratin 10 (CK10) was found to be expressed differently in human
hepatocellular carcinoma (HCC) cell lines with different metastatic potentials in our previous …

Pancreatic cancer is a highly aggressive malignancy that features high recurrence rates and
the poorest prognosis of all solid cancers. The urokinase plasminogen activation system …

The structural proteins cytokeratin 18 (CK18) and its coexpressed complementary partner
CK8 are expressed in a variety of adult epithelial organs and may play a role in …

Keratins are a diverse group of structural proteins that form the intermediate filament network
responsible for maintaining the structural integrity of keratinocytes. In humans, there are …

Sakamoto K, Aragaki T, Morita K‐i, Kawachi H, Kayamori K, Nakanishi S, Omura K, Miki Y,
Okada N, Katsube K‐i, Takizawa T & Yamaguchi A (2011) Histopathology58, 531–542 …