Cell death in photodynamic therapy: From oxidative stress to anti-tumor immunity

C Donohoe, MO Senge, LG Arnaut… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Photodynamic therapy is a promising approach for cancer treatment that relies on the
administration of a photosensitizer followed by tumor illumination. The generated oxidative …

New designs for phototherapeutic transition metal complexes

C Imberti, P Zhang, H Huang… - Angewandte Chemie …, 2020 - Wiley Online Library
In this Minireview, we highlight recent advances in the design of transition metal complexes
for photodynamic therapy (PDT) and photoactivated chemotherapy (PACT), and discuss the …

Oncologic photodynamic therapy: basic principles, current clinical status and future directions

D Van Straten, V Mashayekhi, HS De Bruijn, S Oliveira… - Cancers, 2017 - mdpi.com
Photodynamic therapy (PDT) is a clinically approved cancer therapy, based on a
photochemical reaction between a light activatable molecule or photosensitizer, light, and …

Metal-based photosensitizers for photodynamic therapy: the future of multimodal oncology?

SA McFarland, A Mandel, R Dumoulin-White… - Current opinion in …, 2020 - Elsevier
Photodynamic therapy (PDT) is an approved medical technique to treat certain forms of
cancer. It has been used to complement traditional anticancer modalities such as surgery …

Combination of light and Ru (II) polypyridyl complexes: Recent advances in the development of new anticancer drugs

L Conti, E Macedi, C Giorgi, B Valtancoli… - Coordination Chemistry …, 2022 - Elsevier
The increasing impact of cancer on worldwide mortality makes the research of novel
chemotherapeutic agents a current and challenging issue. In the recent years, transition …

[HTML][HTML] Ru (II)-modified TiO2 nanoparticles for hypoxia-adaptive photo-immunotherapy of oral squamous cell carcinoma

JY Zhou, WJ Wang, CY Zhang, YY Ling, XJ Hong, Q Su… - Biomaterials, 2022 - Elsevier
The alternations in the hypoxic and immune microenvironment are closely related to the
therapeutic effect and prognosis of oral squamous cell carcinoma (OSCC). Herein, a new …

Photodynamic therapy (PDT) of cancer: from local to systemic treatment

JM Dąbrowski, LG Arnaut - Photochemical & Photobiological Sciences, 2015 - pubs.rsc.org
Photodynamic therapy (PDT) requires a medical device, a photosensitizing drug and
adequate use of both to trigger biological mechanisms that can rapidly destroy the primary …

The role of porphyrin chemistry in tumor imaging and photodynamic therapy

M Ethirajan, Y Chen, P Joshi, RK Pandey - Chemical Society Reviews, 2011 - pubs.rsc.org
In recent years several review articles and books have been published on the use of
porphyrin-based compounds in photodynamic therapy (PDT). This critical review is focused …

The physics, biophysics and technology of photodynamic therapy

BC Wilson, MS Patterson - Physics in Medicine & Biology, 2008 - iopscience.iop.org
Photodynamic therapy (PDT) uses light-activated drugs to treat diseases ranging from
cancer to age-related macular degeneration and antibiotic-resistant infections. This paper …

High-resolution optoacoustic imaging of tissue responses to vascular-targeted therapies

K Haedicke, L Agemy, M Omar, A Berezhnoi… - Nature biomedical …, 2020 - nature.com
The monitoring of vascular-targeted therapies using magnetic resonance imaging,
computed tomography or ultrasound is limited by their insufficient spatial resolution. Here, by …