Genetic predisposition to multiple sclerosis (MS) only explains a fraction of the disease risk;
lifestyle and environmental factors are key contributors to the risk of MS. Importantly, these …

Epstein-Barr virus (EBV), also known as human herpesvirus 4, is a double-stranded DNA
virus that is ubiquitous in 90–95% of the population as a gamma herpesvirus. It exists in two …

Lifestyle and environmental factors potently influence the risk of multiple sclerosis (MS),
because genetic predisposition only explains a fraction of the risk increase. There is strong …

Multiple sclerosis (MS) is a disease of the central nervous system characterized by
inflammation, demyelination, and neuronal damage. Environmental and genetic factors are …

PURPOSE OF REVIEW This article summarizes recent advances in the identification of
genetic and environmental factors that affect the risk of developing multiple sclerosis (MS) …

Compelling evidence indicates that Epstein Barr virus (EBV) infection is a prerequisite for
multiple sclerosis (MS). The disease may arise from a complex interplay between latent EBV …

Abstract Immune responses to Epstein–Barr virus (EBV) infection synergize with the main
genetic risk factor HLA‐DRB1* 15: 01 (HLA‐DR15) to increase the likelihood to develop the …

Epstein-Barr virus (EBV) infection has been advocated as a prerequisite for developing
multiple sclerosis (MS) and possibly the propagation of the disease. However, the precise …

Multiple sclerosis (MS) is known to be a partially heritable autoimmune disease. The risk of
developing MS increases from typically 1 in 1,000 in the normal population to 1 in 4 or so for …

Autoimmunity refers to an organism's immune response against its own healthy cells,
tissues, or components, potentially leading to irreversible damage to vital organs. Central …