Cells use the actin cytoskeleton for many of their functions, including their division,
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …

Fascin actin-bundling protein 1 (FSCN1) is a highly conserved actin-bundling protein that
cross links F-actin microfilaments into tight, parallel bundles. Elevated FSCN1 levels have …

Ferroptosis, which is characterized by intracellular iron accumulation and lipid peroxidation,
is a newly described form of regulated cell death that may play a key role in tumour …

Simple Summary Cell migration is an essential biological process that regulates both
development and diseases, such as cancer metastasis. Therefore, understanding the factors …

Fascin is an important regulator of F-actin bundling leading to enhanced filopodia assembly.
Fascin is also overexpressed in most solid tumours where it supports invasion through …

Simple Summary Amino acid transporters play a multifaceted role in tumor initiation,
progression, and therapy resistance. They are critical to cover the high energetic and …

Cancer cell migration and metastasis are the biggest problems in the treatment of cancer
patients. The most aggressive breast cancer (BC) is the triple-negative type. Therefore …

Laryngeal squamous cell carcinoma (LSCC) is a common malignant tumor with a poor
prognosis. Fascin actin‑bundling protein 1 (FSCN1) has been reported to play a crucial role …

Simple Summary Fascin, an actin-binding protein, is upregulated in different types of human
cancers. It is reportedly responsible for increasing the invasive and metastatic ability of …

Inadequate trophoblast proliferation, shallow invasion and exaggerated rate of trophoblast
apoptosis are implicated in early recurrent miscarriage (ERM). However, the mechanistic …