Multiphoton microscopy has rapidly gained popularity in biomedical imaging and materials
science because of its ability to provide three-dimensional images at high spatial and …

The quest for ultrahigh detection sensitivity with spectroscopic contrasts other than
fluorescence has led to various novel approaches to optical microscopy of biological …

Label-free chemical contrast is highly desirable in biomedical imaging. Spontaneous
Raman microscopy provides specific vibrational signatures of chemical bonds, but is often …

The preparation, staining, visualization and interpretation of histological images of tissue is
well accepted as the gold standard process for the diagnosis of disease. These methods …

Raman microscopy is a quantitative, label-free, and noninvasive optical imaging technique
for studying inhomogeneous systems. However, the feebleness of Raman scattering …

Photoacoustic (optoacoustic) tomography, combining optical absorption contrast and highly
scalable spatial resolution (from micrometer optical resolution to millimeter acoustic …

Stimulated Raman scattering (SRS) microscopy is a newly developed label-free chemical
imaging technique that overcomes the speed limitation of confocal Raman microscopy while …

Fluorescence, that is, spontaneous emission, is generally more sensitive than absorption
measurement, and is widely used in optical imaging,. However, many chromophores, such …

Ultrafast optical microscopy, generally employed by incorporating ultrafast laser pulses into
microscopes, can provide spatially resolved mechanistic insight into scientific problems …

Because each nonlinear optical (NLO) imaging modality is sensitive to specific molecules or
structures, multimodal NLO imaging capitalizes the potential of NLO microscopy for studies …