Titanium nanorods loaded PCL meshes with enhanced blood vessel formation and cell migration for wound dressing applications

R Augustine, A Hasan, NK Patan… - Macromolecular …, 2019 - Wiley Online Library
Proper management of nonhealing wounds is an imperative clinical challenge. For the
effective healing of chronic wounds, suitable wound coverage materials with the capability to …

Biodegradable zwitterionic nanoparticles with tunable UCST-type phase separation under physiological conditions

M Sponchioni, PR Bassam, D Moscatelli, P Arosio… - Nanoscale, 2019 - pubs.rsc.org
Thermo-responsive polymeric nanoparticles (NPs) are emerging as a powerful tool in
nanomedicine for the fabrication of advanced drug delivery systems. In addition to their size …

Biodegradable polymeric nanoparticles administered in the cerebrospinal fluid: Brain biodistribution, preferential internalization in microglia and implications for cell …

M Peviani, UC Palmiero, F Cecere, R Milazzo… - Biomaterials, 2019 - Elsevier
Cell-selective drug release in the central nervous system (CNS) holds great promise for the
treatment of many CNS disorders but it is still challenging. We previously demonstrated that …

Magnetite nanoparticles coated with biodegradable zwitterionic polymers as multifunctional nanocomposites for drug delivery and cancer treatment

CJ Perecin, M Sponchioni, R Auriemma… - ACS Applied Nano …, 2022 - ACS Publications
Tailor-made materials for biomedical applications can be constructed with different building
blocks to confer multiple functions on one platform. Here, we demonstrate the facile …

Monitoring the fate of orally administered PLGA nanoformulation for local delivery of therapeutic drugs

L Morelli, S Gimondi, M Sevieri, L Salvioni, M Guizzetti… - Pharmaceutics, 2019 - mdpi.com
One of the goals of the pharmaceutical sciences is the amelioration of targeted drug
delivery. In this context, nanocarrier-dependent transportation represents an ideal method …

Preformed biodegradable zwitterionic nanoparticles as tunable excipients for the formulation of therapeutics directly at the point of care

R Auriemma, M Sponchioni, S Lotti… - Industrial & …, 2021 - ACS Publications
Polyester-based nanoparticles (NPs) are among the most adopted drug delivery systems
developed so far. This is mainly due to their ability to increase the bioavailability of the …

Hierarchically structured protein-based hollow-nanospheres for drug delivery

S Lotfalian, A Nematollahzadeh, S Ghasemi - Reactive and Functional …, 2021 - Elsevier
In this study, bovine serum albumin (BSA) hollow-nano-spheres (HNS) were synthesized as
nano-carriers for paclitaxel (PTX) as model drug. Hierarchically, first, the exterior surface of …

Synthesis of a Diapocynin Prodrug for Its Prolonged Release from Zwitterionic Biodegradable Nanoparticles

R Auriemma, M Sponchioni… - Macromolecular …, 2021 - Wiley Online Library
Today, neurodegenerative diseases are affecting more and more individuals. A typical
therapeutic target to treat the progression of the symptoms related to these diseases is the …

Versatile, Highly Controlled Synthesis of Hybrid (Meth) acrylate–Polyester–Carbonates and their Exploitation in Tandem Post‐Polymerization–Functionalization

AK Pearce, CE Vasey, AB Anane‐Adjei… - Macromolecular …, 2019 - Wiley Online Library
Abstract The use of 1, 8‐diazabicyclo [5.4. 0] undec‐7‐ene (DBU) as a mild catalyst for the
ring‐opening polymerization (ROP) of the pharma‐friendly and biodegradable monomer …

[引用][C] Fabrication and Evaluation of Redox Micellar nanocarriers for Intracellular Delivery in Solid Tumor Therapy

S RAZZAQ - 2021 - Quaid i Azam University