[HTML][HTML] Stabilizing vaccines via drying: Quality by design considerations

Z Ghaemmaghamian, R Zarghami, G Walker… - Advanced Drug Delivery …, 2022 - Elsevier
Pandemics and epidemics are continually challenging human beings' health and imposing
major stresses on the societies particularly over the last few decades, when their frequency …

Spray drying for direct compression of pharmaceuticals

N Al-Zoubi, S Gharaibeh, A Aljaberi, I Nikolakakis - Processes, 2021 - mdpi.com
Tableting by direct compression (DC) is one of the simplest and most cost-effective drug
manufacturing approaches. However, most active pharmaceutical ingredients (APIs) and …

Facile synthesis of manganese oxide modified lignin nanocomposites from lignocellulosic biorefinery wastes for dye removal

R Zhai, J Hu, X Chen, Z Xu, Z Wen, M Jin - Bioresource Technology, 2020 - Elsevier
In this study, a facile method to prepare MnO 2 nanodots modified lignin nanocomposite
(MnO 2@ LNP) was developed for efficient dye removal. The MnO 2@ LNP displayed …

Influences of different microcrystalline cellulose (MCC) grades on tablet quality and compression behavior of MCC-lactose binary mixtures

H Zhao, C Shi, L Zhao, Y Wang, L Shen - Journal of Drug Delivery Science …, 2022 - Elsevier
Microcrystalline cellulose (MCC) is one of the most commonly used excipients in tablet
formulations. At present, numerous grades of MCC are available for pharmaceutical …

Attribute transmission and effects of diluents and granulation liquids on granule properties and tablet quality for high shear wet granulation and tableting process

LF Wang, LJ Zhao, YL Hong, L Shen, X Lin - International Journal of …, 2023 - Elsevier
This study aims to examine (i) the effect of diluent types (lactose monohydrate, corn starch,
and microcrystalline cellulose) and granulation liquids (20% polyvinylpyrrolidone K30, 65 …

Amorphous solid dispersion of ibuprofen: A comparative study on the effect of solution based techniques

A Ziaee, S O'Dea, A Howard-Hildige, L Padrela… - International journal of …, 2019 - Elsevier
Amorphous solid dispersion (ASD) is one of the most promising strategies for improving the
solubility of active pharmaceutical ingredients (APIs) with low aqueous solubility. Solvent …

Research on the powder classification and the key parameters affecting tablet qualities for direct compaction based on powder functional properties

Y Yu, L Zhao, X Lin, Y Wang, R Du, Y Feng - Advanced Powder …, 2021 - Elsevier
Direct compaction (DC) is the ideal method for tablet production. However, DC requires the
highest quality powder functional properties, such as good flowability, compressibility …

A model to simultaneously evaluate the compressibility and compactibility of a powder based on the compression ratio

Y Yu, L Zhao, X Lin, Y Wang, Y Feng - International Journal of …, 2020 - Elsevier
The present study aimed to establish a new model to evaluate the compressibility and
compactibility of materials simultaneously. Eighteen types of pharmaceutical excipients were …

[HTML][HTML] Insights into the ameliorating ability of mesoporous silica in modulating drug release in ternary amorphous solid dispersion prepared by hot melt extrusion

S Solomon, J Iqbal, AB Albadarin - European Journal of Pharmaceutics and …, 2021 - Elsevier
In this work, the application of various mesoporous silica grades in the preparation of
stabilized ternary amorphous solid dispersions of Felodipine using hot melt extrusion was …

Surface modifiers on composite particles for direct compaction

FC Chen, WJ Liu, WF Zhu, LY Yang, JW Zhang, Y Feng… - Pharmaceutics, 2022 - mdpi.com
Direct compaction (DC) is considered to be the most effective method of tablet production.
However, only a small number of the active pharmaceutical ingredients (APIs) can be …