Diabetes insipidus
M Christ-Crain, DG Bichet, WK Fenske… - Nature reviews Disease …, 2019 - nature.com
Diabetes insipidus (DI) is a disorder characterized by excretion of large amounts of
hypotonic urine. Central DI results from a deficiency of the hormone arginine vasopressin …
hypotonic urine. Central DI results from a deficiency of the hormone arginine vasopressin …
Molecular physiology of water balance
MA Knepper, TH Kwon, S Nielsen - New England Journal of …, 2015 - Mass Medical Soc
Molecular Physiology of Water Balance | New England Journal of Medicine Skip to main content
The New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
The New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
Pathophysiology, diagnosis and management of nephrogenic diabetes insipidus
D Bockenhauer, DG Bichet - Nature Reviews Nephrology, 2015 - nature.com
Healthy kidneys maintain fluid and electrolyte homoeostasis by adjusting urine volume and
composition according to physiological needs. The final urine composition is determined in …
composition according to physiological needs. The final urine composition is determined in …
Aquaporin 2 regulation: implications for water balance and polycystic kidney diseases
ETB Olesen, RA Fenton - Nature Reviews Nephrology, 2021 - nature.com
Targeting the collecting duct water channel aquaporin 2 (AQP2) to the plasma membrane is
essential for the maintenance of mammalian water homeostasis. The vasopressin V2 …
essential for the maintenance of mammalian water homeostasis. The vasopressin V2 …
Nephrogenic diabetes insipidus: essential insights into the molecular background and potential therapies for treatment
The water channel aquaporin-2 (AQP2), expressed in the kidney collecting ducts, plays a
pivotal role in maintaining body water balance. The channel is regulated by the peptide …
pivotal role in maintaining body water balance. The channel is regulated by the peptide …
Renal aquaporins and water balance disorders
MLA Kortenoeven, RA Fenton - … et Biophysica Acta (BBA)-General Subjects, 2014 - Elsevier
Abstract Background Aquaporins (AQPs) are a family of proteins that can act as water
channels. Regulation of AQPs is critical to osmoregulation and the maintenance of body …
channels. Regulation of AQPs is critical to osmoregulation and the maintenance of body …
Molecular biology of aquaporins
C Li, W Wang - Aquaporins, 2017 - Springer
Aquaporins (AQPs) are a family of membrane water channels that basically function as
regulators of intracellular and intercellular water flow. To date, thirteen AQPs, which are …
regulators of intracellular and intercellular water flow. To date, thirteen AQPs, which are …
Molecular mechanisms regulating aquaporin-2 in kidney collecting duct
The kidney collecting duct is an important renal tubular segment for regulation of body water
homeostasis and urine concentration. Water reabsorption in the collecting duct principal …
homeostasis and urine concentration. Water reabsorption in the collecting duct principal …
Vasopressin and the regulation of aquaporin-2
JLL Wilson, CA Miranda, MA Knepper - Clinical and experimental …, 2013 - Springer
Water excretion is regulated in large part through the regulation of osmotic water
permeability of the renal collecting duct epithelium. Water permeability is controlled by …
permeability of the renal collecting duct epithelium. Water permeability is controlled by …
Phosphorylation influences water and ion channel function of AtPIP2; 1
The phosphorylation state of two serine residues within the C‐terminal domain of AtPIP2; 1
(S280, S283) regulates its plasma membrane localization in response to salt and osmotic …
(S280, S283) regulates its plasma membrane localization in response to salt and osmotic …