Vasculogenic mimicry formation in EBV-associated epithelial malignancies

T Xiang, YX Lin, W Ma, HJ Zhang, KM Chen… - Nature …, 2018 - nature.com
Abstract Epstein-Barr virus (EBV)-associated epithelial cancers, including nasopharyngeal
carcinoma (NPC) and approximately 10% of gastric cancers, termed EBVaGC, represent …

Current approach and novel perspectives in nasopharyngeal carcinoma: the role of targeting proteasome dysregulation as a molecular landmark in nasopharyngeal …

R Yarza, M Bover, MT Agulló-Ortuño… - Journal of Experimental …, 2021 - Springer
Nasopharyngeal carcinoma (NPC) represents a molecularly paradigmatic tumor given the
complex diversity of environmental as well as host dependent factors that are closely …

The central role of the ubiquitin–proteasome system in EBV-mediated oncogenesis

Y Pei, ES Robertson - Cancers, 2022 - mdpi.com
Simple Summary Epstein–Barr virus (EBV) is the first discovered human tumor virus, which
contributes to the oncogenesis of many human cancers. The ubiquitin–proteasome system …

Analysis of the tropism of SARS-CoV-2 based on the host interactome of the spike protein

C Bamberger, S Pankow… - Journal of Proteome …, 2023 - ACS Publications
The β-coronavirus SARS-CoV-2 causes severe acute respiratory syndrome (COVID-19) in
humans. It enters and infects epithelial airway cells upon binding of the receptor binding …

Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection

J Hong, L Zhong, L Liu, Q Wu, W Zhang, K Chen… - Cell Reports …, 2023 - cell.com
Epstein-Barr virus (EBV) is closely associated with cancer, multiple sclerosis, and post-acute
coronavirus disease 2019 (COVID-19) sequelae. There are currently no approved …

SARS-CoV-2 activates ER stress and Unfolded protein response

L Rosa-Fernandes, LC Lazari, JM da Silva… - BioRxiv, 2021 - biorxiv.org
ABSTRACT Coronavirus disease-2019 (COVID-19) pandemic caused by the SARS-CoV-2
coronavirus infection is a major global public health concern affecting millions of people …

A cocktail nanovaccine targeting key entry glycoproteins elicits high neutralizing antibody levels against EBV infection

L Zhong, W Zhang, H Liu, X Zhang, Z Yang… - Nature …, 2024 - nature.com
Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is closely
associated with various malignancies. Considering the complex life cycle of EBV …

A Neutralizing Antibody Targeting gH Provides Potent Protection against EBV Challenge In Vivo

J Hong, L Zhong, Q Zheng, Q Wu, Z Zha, D Wei… - Journal of …, 2022 - Am Soc Microbiol
Epstein-Barr virus (EBV) is an oncogenic herpesvirus that is associated with 200,000 new
cases of cancer and 140,000 deaths annually. To date, there are no available vaccines or …

SHROOM2 inhibits tumor metastasis through RhoA–ROCK pathway-dependent and-independent mechanisms in nasopharyngeal carcinoma

J Yuan, L Chen, J Xiao, XK Qi, J Zhang, X Li… - Cell death & …, 2019 - nature.com
SHROOM2 is a key mediator of RhoA–ROCK pathway that regulates cell motility and actin
cytoskeleton organization. However, the functions of SHROOM2 beyond RhoA/ROCK …

Multiplex assays reveal anti‐EBV antibody profile and its implication in detection and diagnosis of nasopharyngeal carcinoma

L Ma, TM Wang, YQ He, Y Liao, X Yan… - … Journal of Cancer, 2024 - Wiley Online Library
Epstein–Barr virus (EBV) is detected in nearly 100% of nonkeratinizing nasopharyngeal
carcinoma (NPC) and EBV‐based biomarkers are used for NPC screening in endemic …