Background Fentanyl and non-pharmaceutical fentanyls (NPFs) have been responsible for
numerous outbreaks of overdoses all over the United States since the 1970s. However …

Purpose This systematic review summarizes and presents the current state of research
quantifying the relationship between mental disorder and overdose for people who use …

Background: The Centers for Disease Control and Prevention recognizes Medicaid as a
high-risk population for fatal opioid overdose. Further research is needed to identify factors …

From April 2020 through April 2021, 75,673 Americans died from opioid overdoses, nearly
one-quarter of which directly involved prescription opioids. 1 This represents the first time …

Study objective Persons with substance use disorders frequently utilize emergency
department (ED) services, creating an opportunity for intervention and referral to addiction …

Worldwide, 80% of patients who undergo surgery receive opioid analgesics as the
fundamental agent for pain relief. However, the irrational use of opioids leads to excessive …

The net effects of prescribing initiatives that encourage dose reductions are uncertain. We
examined whether rapid dose reduction after high-dose chronic opioid therapy (COT) …

Background Drug overdose is a public health crisis in the United States, due in part to the
unintended consequences of increases in prescribing of opioid analgesics. Many clinicians …

Background Opioid overdose deaths have continued to rise in Tennessee (TN) with fentanyl
emerging as a major contributor. Current data are needed to identify at-risk populations to …

Background The rate of an unintentional drug overdose involving prescription opioids
continues to rise. An understanding of the threshold dose and dose (s) associated with …