In response to mechanical forces and the aging process, bone in the adult skeleton is
continuously remodeled by a process in which old and damaged bone is removed by bone …

Abstract Purpose of Review The purpose of this article is to review the current understanding
of inflammatory processes on bone, including direct impacts of inflammatory factors on bone …

The periosteum is the major source of cells involved in fracture healing. We sought to
characterize progenitor cells and their contribution to bone fracture healing. The periosteum …

Rheumatoid arthritis (RA) is a systemic autoimmune disease that primarily affects the joints.
Organokines can produce beneficial or harmful effects in this condition. Among RA patients …

Osteoporosis poses substantial challenges for biomaterials implantation. New approaches
to improve bone‐implant integration should resolve the fundamental dilemma of …

Cell-based cartilage tissue engineering faces a great challenge in the repair process, partly
due to the special physical microenvironment. Human stem cell from apical papilla (hSCAP) …

Background: Bone morphogenetic protein 2 (BMP2) is an appealing osteogenic and
chondrogenic growth factor for promoting tendon-bone healing. Recently, it has been …

Objectives Our study profiled the CD4+ T-cell-derived exosomes from patients with
rheumatoid arthritis (RA) using proteomics. Methods Proteomic analysis of CD4+ T-cell …

Bone remodeling occurs through the interactions of three major cell lineages, osteoblasts,
which mediate bone formation, osteocytes, which derive from osteoblasts, sense mechanical …

Introduction: Currently, there are no non-surgical FDA-approved biological approaches to
accelerate fracture repair. Injectable therapies designed to stimulate bone healing represent …