The vaginal microbiota, host defence and reproductive physiology
The interaction between the human host and the vaginal microbiota is highly dynamic. Major
changes in the vaginal physiology and microbiota over a woman's lifetime are largely …
changes in the vaginal physiology and microbiota over a woman's lifetime are largely …
SP-A and SP-D: dual functioning immune molecules with antiviral and immunomodulatory properties
Surfactant proteins A (SP-A) and D (SP-D) are soluble innate immune molecules which
maintain lung homeostasis through their dual roles as anti-infectious and …
maintain lung homeostasis through their dual roles as anti-infectious and …
The role of surfactant in lung disease and host defense against pulmonary infections
SH Han, RK Mallampalli - Annals of the American Thoracic Society, 2015 - atsjournals.org
Pulmonary surfactant is essential for life as it lines the alveoli to lower surface tension,
thereby preventing atelectasis during breathing. Surfactant is enriched with a relatively …
thereby preventing atelectasis during breathing. Surfactant is enriched with a relatively …
Surfactant protein D in respiratory and non-respiratory diseases
GL Sorensen - Frontiers in medicine, 2018 - frontiersin.org
Surfactant protein D (SP-D) is a multimeric collectin that is involved in innate immune
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …
defense and expressed in pulmonary, as well as non-pulmonary, epithelia. SP-D exerts …
Pathogenesis of HIV-related lung disease: immunity, infection, and inflammation
SK Cribbs, K Crothers, A Morris - Physiological reviews, 2020 - journals.physiology.org
Despite anti-retroviral therapy (ART), human immunodeficiency virus-1 (HIV)-related
pulmonary disease continues to be a major cause of morbidity and mortality for people living …
pulmonary disease continues to be a major cause of morbidity and mortality for people living …
Human surfactant protein D binds spike protein and acts as an entry inhibitor of SARS-CoV-2 pseudotyped viral particles
MH Hsieh, N Beirag, V Murugaiah, YC Chou… - Frontiers in …, 2021 - frontiersin.org
Human SP-D is a potent innate immune molecule whose presence at pulmonary mucosal
surfaces allows its role in immune surveillance against pathogens. Higher levels of serum …
surfaces allows its role in immune surveillance against pathogens. Higher levels of serum …
Human lectins and their roles in viral infections
CP Mason, AW Tarr - Molecules, 2015 - mdpi.com
Innate recognition of virus proteins is an important component of the immune response to
viral pathogens. A component of this immune recognition is the family of lectins; pattern …
viral pathogens. A component of this immune recognition is the family of lectins; pattern …
A recombinant fragment of human surfactant protein D binds spike protein and inhibits infectivity and replication of SARS-CoV-2 in clinical samples
T Madan, B Biswas, PM Varghese… - American journal of …, 2021 - atsjournals.org
Coronavirus disease (COVID-19) is an acute infectious disease caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Human SP-D (surfactant protein D) is …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Human SP-D (surfactant protein D) is …
[HTML][HTML] Surfactant proteins A and D: trimerized innate immunity proteins with an affinity for viral fusion proteins
Innate recognition of viruses is an essential part of the immune response to viral pathogens.
This is integral to the maintenance of healthy lungs, which are free from infection and …
This is integral to the maintenance of healthy lungs, which are free from infection and …
Collectins: innate immune pattern recognition molecules
Collectins are collagen-containing C-type (calcium-dependent) lectins which are important
pathogen pattern recognising innate immune molecules. Their primary structure is …
pathogen pattern recognising innate immune molecules. Their primary structure is …