Novel experimental approaches such as fate-mapping and single-cell analysis have brought
fresh insight into monocyte development and function over the past decade and helped …

Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …

Paradigm-shifting studies in the mouse have identified tissue macrophage heterogeneity as
a critical determinant of immune responses. In contrast, surprisingly little is known regarding …

In humans, the monocyte pool comprises three subsets (classical, intermediate, and
nonclassical) that circulate in dynamic equilibrium. The kinetics underlying their generation …

Studies on monocyte and macrophage biology and differentiation have revealed the
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …

Human monocytes have been grouped into classical (CD14++ CD16−), non-classical
(CD14dimCD16++), and intermediate (CD14++ CD16+) subsets. Documentation of normal …

Myeloid cells are a significant proportion of leukocytes within tissues, comprising
granulocytes, monocytes, dendritic cells, and macrophages. With the identification of various …

The mononuclear phagocyte system (MPS) has historically been categorized into
monocytes, dendritic cells and macrophages on the basis of functional and phenotypical …

Macrophages are immune cells of haematopoietic origin that provide crucial innate immune
defence and have tissue-specific functions in the regulation and maintenance of organ …

Macrophages, the most plastic cells of the haematopoietic system, are found in all tissues
and show great functional diversity. They have roles in development, homeostasis, tissue …