Anemia and iron deficiency in heart failure: current concepts and emerging therapies

IS Anand, P Gupta - Circulation, 2018 - Am Heart Assoc
Anemia and iron deficiency are important and common comorbidities that often coexist in
patients with heart failure. Both conditions, together or independently, are associated with …

Iron deficiency in heart failure: an overview

S von Haehling, N Ebner, R Evertz, P Ponikowski… - JACC: Heart Failure, 2019 - jacc.org
Iron deficiency is an extremely common comorbidity in patients with heart failure, affecting
up to 50% of all ambulatory patients. It is associated with reduced exercise capacity and …

Preoperative intravenous iron to treat anaemia before major abdominal surgery (PREVENTT): a randomised, double-blind, controlled trial

T Richards, RR Baikady, B Clevenger, A Butcher… - The Lancet, 2020 - thelancet.com
Background Preoperative anaemia affects a high proportion of patients undergoing major
elective surgery and is associated with poor outcomes. We aimed to test the hypothesis that …

[HTML][HTML] Iron bioavailability and dietary reference values

R Hurrell, I Egli - The American journal of clinical nutrition, 2010 - Elsevier
Iron differs from other minerals because iron balance in the human body is regulated by
absorption only because there is no physiologic mechanism for excretion. On the basis of …

Iron deficiency and cardiovascular disease

S Von Haehling, EA Jankowska… - Nature Reviews …, 2015 - nature.com
Iron deficiency affects up to one-third of the world's population, and is particularly common in
elderly individuals and those with certain chronic diseases. Iron excess can be detrimental …

Immunoassay for human serum hepcidin

T Ganz, G Olbina, D Girelli, E Nemeth… - Blood, The Journal …, 2008 - ashpublications.org
We developed and validated the first serum enzyme-linked immunosorbent assay for
hepcidin, the principal iron-regulatory hormone that has been very difficult to measure. In …

Clinical practice guideline: red blood cell transfusion in adult trauma and critical care

LM Napolitano, S Kurek, FA Luchette… - Critical care …, 2009 - journals.lww.com
Objective: To develop a clinical practice guideline for red blood cell transfusion in adult
trauma and critical care. Design: Meetings, teleconferences and electronic-based …

Anaemia, iron deficiency and heart failure in 2020: facts and numbers

VK Chopra, SD Anker - ESC heart failure, 2020 - Wiley Online Library
Anaemia is defined by WHO as Hb< 13.0 g/dL in male adults and< 12.0 g/dL in female
adults. It is a common comorbidity in patients of heart failure with both HFrEF and HFpEF …

Intracellular iron transport and storage: from molecular mechanisms to health implications

EL Mackenzie, K Iwasaki, Y Tsuji - Antioxidants & redox signaling, 2008 - liebertpub.com
Maintenance of proper “labile iron” levels is a critical component in preserving homeostasis.
Iron is a vital element that is a constituent of a number of important macromolecules …

[HTML][HTML] Iron in fatty liver and in the metabolic syndrome: a promising therapeutic target

P Dongiovanni, AL Fracanzani, S Fargion, L Valenti - Journal of hepatology, 2011 - Elsevier
The dysmetabolic iron overload syndrome (DIOS) is now a frequent finding in the general
population, as is detected in about one third of patients with nonalcoholic fatty liver disease …