Circulating endocannabinoids: from whence do they come and where are they going?
CJ Hillard - Neuropsychopharmacology, 2018 - nature.com
The goal of this review is to summarize studies in which concentrations of circulating
endocannabinoids in humans have been examined in relationship to physiological …
endocannabinoids in humans have been examined in relationship to physiological …
Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication
JB Funcke, PE Scherer - Journal of lipid research, 2019 - ASBMB
The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …
Pharmacotherapy of obesity: available medications and drugs under investigation
Obesity is a chronic disease with a continuously rising prevalence that currently affects more
than half a billion people worldwide. Energy balance and appetite are highly regulated via …
than half a billion people worldwide. Energy balance and appetite are highly regulated via …
Molecular basis of the beneficial actions of resveratrol
G Repossi, UN Das, AR Eynard - Archives of medical research, 2020 - Elsevier
Resveratrol modulates the transcription factor NF-κB, cytochrome P450 isoenzyme CYP1A1,
expression and activity of cyclooxygenase (COX) enzymes, Fas/Fas ligand mediated …
expression and activity of cyclooxygenase (COX) enzymes, Fas/Fas ligand mediated …
The critical role of CCK in the regulation of food intake and diet-induced obesity
CR Cawthon, CB de La Serre - Peptides, 2021 - Elsevier
Abstract In 1973, Gibbs, Young, and Smith showed that exogenous cholecystokinin (CCK)
administration reduces food intake in rats. This initial report has led to thousands of studies …
administration reduces food intake in rats. This initial report has led to thousands of studies …
Mediterranean versus Western diet effects on caloric intake, obesity, metabolism, and hepatosteatosis in nonhuman primates
CA Shively, SE Appt, MZ Vitolins, B Uberseder… - …, 2019 - Wiley Online Library
Objective This study aimed to determine the effects of humanlike Western and
Mediterranean diets on caloric intake, obesity, metabolism, and hepatosteatosis in an …
Mediterranean diets on caloric intake, obesity, metabolism, and hepatosteatosis in an …
Endocannabinoid modulation of homeostatic and non-homeostatic feeding circuits
The endocannabinoid system has emerged as a key player in the control of eating.
Endocannabinoids, including 2-arachidonoylglycerol (2-AG) and anandamide (AEA) …
Endocannabinoids, including 2-arachidonoylglycerol (2-AG) and anandamide (AEA) …
Involvement of TRPV1 channels in energy homeostasis
The ion channel TRPV1 is involved in a wide range of processes including nociception,
thermosensation and, more recently discovered, energy homeostasis. Tightly controlling …
thermosensation and, more recently discovered, energy homeostasis. Tightly controlling …
Theoretical Explanation for Reduced Body Mass Index and Obesity Rates in Cannabis Users
TM Clark, JM Jones, AG Hall, SA Tabner… - Cannabis and …, 2018 - liebertpub.com
Introduction: Obesity is treatment-resistant, and is linked with a number of serious, chronic
diseases. Adult obesity rates in the United States have tripled since the early 1960s. Recent …
diseases. Adult obesity rates in the United States have tripled since the early 1960s. Recent …
Overcoming the psychiatric side effects of the cannabinoid CB1 receptor antagonists: current approaches for therapeutics development
The Cannabinoid CB1 Receptor (CB1R) is involved in a variety of physiological pathways
and has long been considered a golden target for therapeutic manipulation. A large body of …
and has long been considered a golden target for therapeutic manipulation. A large body of …