When does Alzheimer′ s disease really start? The role of biomarkers

A Lloret, D Esteve, MA Lloret, A Cervera-Ferri… - International journal of …, 2019 - mdpi.com
While Alzheimer's disease (AD) classical diagnostic criteria rely on clinical data from a
stablished symptomatic disease, newer criteria aim to identify the disease in its earlier …

Trustworthy artificial intelligence in Alzheimer's disease: state of the art, opportunities, and challenges

S El-Sappagh, JM Alonso-Moral, T Abuhmed… - Artificial Intelligence …, 2023 - Springer
Abstract Medical applications of Artificial Intelligence (AI) have consistently shown
remarkable performance in providing medical professionals and patients with support for …

A multilayer multimodal detection and prediction model based on explainable artificial intelligence for Alzheimer's disease

S El-Sappagh, JM Alonso, SMR Islam, AM Sultan… - Scientific reports, 2021 - nature.com
Alzheimer's disease (AD) is the most common type of dementia. Its diagnosis and
progression detection have been intensively studied. Nevertheless, research studies often …

Multimodal multitask deep learning model for Alzheimer's disease progression detection based on time series data

S El-Sappagh, T Abuhmed, SMR Islam, KS Kwak - Neurocomputing, 2020 - Elsevier
Early prediction of Alzheimer's disease (AD) is crucial for delaying its progression. As a
chronic disease, ignoring the temporal dimension of AD data affects the performance of a …

Robust hybrid deep learning models for Alzheimer's progression detection

T Abuhmed, S El-Sappagh, JM Alonso - Knowledge-Based Systems, 2021 - Elsevier
The prevalence of Alzheimer's disease (AD) in the growing elderly population makes
accurately predicting AD progression crucial. Due to AD's complex etiology and …

Dementia detection from speech using machine learning and deep learning architectures

MR Kumar, S Vekkot, S Lalitha, D Gupta, VJ Govindraj… - Sensors, 2022 - mdpi.com
Dementia affects the patient's memory and leads to language impairment. Research has
demonstrated that speech and language deterioration is often a clear indication of dementia …

Improved Alzheimer's disease detection by MRI using multimodal machine learning algorithms

G Battineni, MA Hossain, N Chintalapudi, E Traini… - Diagnostics, 2021 - mdpi.com
Adult-onset dementia disorders represent a challenge for modern medicine. Alzheimer's
disease (AD) represents the most diffused form of adult-onset dementias. For half a century …

A practical computerized decision support system for predicting the severity of Alzheimer's disease of an individual

M Bucholc, X Ding, H Wang, DH Glass, H Wang… - Expert systems with …, 2019 - Elsevier
Computerized clinical decision support systems can help to provide objective, standardized,
and timely dementia diagnosis. However, current computerized systems are mainly based …

Association of the use of hearing aids with the conversion from mild cognitive impairment to dementia and progression of dementia: a longitudinal retrospective study

M Bucholc, PL McClean, S Bauermeister… - … Research & Clinical …, 2021 - Wiley Online Library
Introduction Hearing aid usage has been linked to improvements in cognition,
communication, and socialization, but the extent to which it can affect the incidence and …

Practical strategies for extreme missing data imputation in dementia diagnosis

N McCombe, S Liu, X Ding, G Prasad… - IEEE journal of …, 2021 - ieeexplore.ieee.org
Accurate computational models for clinical decision support systems require clean and
reliable data but, in clinical practice, data are often incomplete. Hence, missing data could …