Exosomes and their noncoding RNA cargo are emerging as new modulators for diabetes mellitus

W Chang, J Wang - Cells, 2019 - mdpi.com
Diabetes belongs to a group of metabolic disorders characterized by long term high blood
glucose levels due to either inadequate production of insulin (Type 1 diabetes, T1DM) or …

Identifying the therapeutic significance of mesenchymal stem cells

VK Mishra, HH Shih, F Parveen, D Lenzen, E Ito… - Cells, 2020 - mdpi.com
The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due
to their immense potential for immunosuppression and their therapeutic role in immune …

Stem cell-derived and circulating exosomal microRNAs as new potential tools for diabetic nephropathy management

L Peng, Y Chen, S Shi, H Wen - Stem Cell Research & Therapy, 2022 - Springer
Background Despite major advances in the treatment of diabetic nephropathy (DN) in recent
years, it remains the most common cause of end-stage renal disease. An early diagnosis …

Extracellular vesicles in type 2 diabetes mellitus: key roles in pathogenesis, complications, and therapy

Y Xiao, L Zheng, X Zou, J Wang, J Zhong… - Journal of extracellular …, 2019 - Taylor & Francis
Type 2 diabetes mellitus (T2DM), a chronic disease, is widely prevalent all over the world. In
recent years, the roles of some extracellular vesicles (EVs) in T2DM have attracted much …

Mesenchymal stem cell-based therapy for retinal degenerative diseases: experimental models and clinical trials

V Holan, K Palacka, B Hermankova - Cells, 2021 - mdpi.com
Retinal degenerative diseases, such as age-related macular degeneration, retinitis
pigmentosa, diabetic retinopathy or glaucoma, represent the main causes of a decreased …

The utility of exosomes in diagnosis and therapy of diabetes mellitus and associated complications

Y Sun, Q Tao, X Wu, L Zhang, Q Liu… - Frontiers in …, 2021 - frontiersin.org
Diabetes mellitus and the associated complications are metabolic diseases with high
morbidity that result in poor quality of health and life. The lack of diagnostic methods for early …

Mesenchymal stem cells and extracellular vesicles in therapy against kidney diseases

Y Huang, L Yang - Stem cell research & therapy, 2021 - Springer
Kidney diseases pose a threat to human health due to their rising incidence and fatality rate.
In preclinical and clinical studies, it has been acknowledged that mesenchymal stem cells …

Mesenchymal stem cell-derived extracellular vesicles: a potential therapy for diabetes mellitus and diabetic complications

F Sun, Y Sun, F Wu, W Xu, H Qian - Pharmaceutics, 2022 - mdpi.com
As a novel cell-free strategy, mesenchymal stem cell-derived extracellular vesicles (MSC-
EVs) inherit the therapeutic potential of donor cells, and are widely used for the treatment of …

Extracellular vesicles secreted from mesenchymal stem cells exert anti-apoptotic and anti-inflammatory effects via transmitting microRNA-18b in rats with diabetic …

Z Xu, N Tian, S Li, K Li, H Guo, H Zhang, H Jin… - International …, 2021 - Elsevier
Diabetic retinopathy (DR) is a major cause of visual deficits and blindness in the working-
age population and inflammatory response is a key event during DR. In this study, we …

Stem Cell therapy in combination with naturopathy: Current progressive management of diabetes and associated complications

A Saha, A Samadder, S Nandi - Current Topics in Medicinal …, 2023 - ingentaconnect.com
Background: Diabetes is a chronic metabolic disorder having a global prevalence of nearly
doubled over the last 30 years and has become one of the major health concerns …