Molecular mechanisms of external genitalia development

SD Blaschko, GR Cunha, LS Baskin - Differentiation, 2012 - Elsevier
External genitalia development occurs through a combination of hormone independent,
hormone dependent, and endocrine pathways. Perturbation of these pathways can lead to …

Formation, structure, and function of extra‐skeletal bones in mammals

A Nasoori - Biological Reviews, 2020 - Wiley Online Library
This review describes the formation, structure, and function of bony compartments in antlers,
horns, ossicones, osteoderm and the os penis/os clitoris (collectively referred to herein as …

Development of the human penis and clitoris

L Baskin, J Shen, A Sinclair, M Cao, X Liu, G Liu… - Differentiation, 2018 - Elsevier
The human penis and clitoris develop from the ambisexual genital tubercle. To compare and
contrast the development of human penis and clitoris, we used macroscopic photography …

Trichomonas vaginalis adherence phenotypes and extracellular vesicles impact parasite survival in a novel in vivo model of pathogenesis

BM Molgora, SK Mukherjee… - PLOS Neglected …, 2023 - journals.plos.org
Trichomonas vaginalis is a human infective parasite responsible for trichomoniasis–the most
common, non-viral, sexually transmitted infection worldwide. T. vaginalis resides exclusively …

An illustrated anatomical ontology of the developing mouse lower urogenital tract

KM Georgas, J Armstrong, JR Keast… - …, 2015 - journals.biologists.com
Malformation of the urogenital tract represents a considerable paediatric burden, with many
defects affecting the lower urinary tract (LUT), genital tubercle and associated structures …

Corpora cavernosa fibroblasts mediate penile erection

EL Guimaraes, DO Dias, WF Hau, A Julien, D Holl… - Science, 2024 - science.org
Penile erection is mediated by the corpora cavernosa, a trabecular-like vascular bed that
enlarges upon vasodilation, but its regulation is not completely understood. Here, we show …

Reproductive tract biology: of mice and men

GR Cunha, A Sinclair, WA Ricke, SJ Robboy, M Cao… - Differentiation, 2019 - Elsevier
The study of male and female reproductive tract development requires expertise in two
separate disciplines, developmental biology and endocrinology. For ease of …

Current understanding of hypospadias: relevance of animal models

GR Cunha, A Sinclair, G Risbridger, J Hutson… - Nature Reviews …, 2015 - nature.com
Hypospadias is a congenital abnormality of the penile urethra with an incidence of
approximately 1: 200–1: 300 male births, which has doubled over the past three decades …

Wound healing responses of urinary extravasation after urethral injury

T Hyuga, K Fujimoto, D Hashimoto, K Tanabe… - Scientific Reports, 2023 - nature.com
The post-surgical fluid leakage from the tubular tissues is a critical symptom after
gastrointestinal or urinary tract surgeries. Elucidating the mechanism for such abnormalities …

Baculum morphology predicts reproductive success of male house mice under sexual selection

P Stockley, SA Ramm, AL Sherborne, MDF Thom… - BMC biology, 2013 - Springer
Background Diversity in penile morphology is characterised by extraordinary variation in the
size and shape of the baculum (penis bone) found in many mammals. Although functionally …