The mucosal immune system of teleost fish

I Salinas - Biology, 2015 - mdpi.com
Teleost fish possess an adaptive immune system associated with each of their mucosal
body surfaces. Evidence obtained from mucosal vaccination and mucosal infection studies …

Advances in research of fish immune-relevant genes: a comparative overview of innate and adaptive immunity in teleosts

L Zhu, L Nie, G Zhu, L Xiang, J Shao - Developmental & Comparative …, 2013 - Elsevier
Fish is considered to be an important model in comparative immunology studies because it
is a representative population of lower vertebrates serving as an essential link to early …

SARS‐CoV‐2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG‐I/MDA‐5–MAVS, TLR3–TRIF, and cGAS–STING signaling …

L Han, MW Zhuang, J Deng, Y Zheng… - Journal of medical …, 2021 - Wiley Online Library
The suppression of types I and III interferon (IFN) responses by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) contributes to the pathogenesis of coronavirus …

Teleost fish interferons and their role in immunity

J Zou, CJ Secombes - Developmental & Comparative Immunology, 2011 - Elsevier
Interferons (IFNs) are the hallmark of the vertebrate antiviral system. Two of the three IFN
families identified in higher vertebrates are now known to be important for antiviral defence …

Toll-like receptor signaling in bony fish

A Rebl, T Goldammer, HM Seyfert - Veterinary immunology and …, 2010 - Elsevier
The innate immune system constitutes an efficient defense against invading microbial
pathogens. Toll-like receptors (TLRs) eventually alert vertebrates about the presence of …

Insights into the Antiviral Immunity against Grass Carp (Ctenopharyngodon idella) Reovirus (GCRV) in Grass Carp

Y Rao, J Su - Journal of Immunology Research, 2015 - Wiley Online Library
Global fish production from aquaculture has rapidly grown over the past decades, and grass
carp shares the largest portion. However, hemorrhagic disease caused by grass carp …

Molecular regulation of interferon antiviral response in fish

YB Zhang, JF Gui - Developmental & Comparative Immunology, 2012 - Elsevier
Interferon (IFN) response is the first line of host defense against virus infection. The recent
years have witnessed tremendous progress in understanding of fish IFN antiviral response …

Pattern recognition receptors in zebrafish provide functional and evolutionary insight into innate immune signaling pathways

Y Li, Y Li, X Cao, X Jin, T Jin - Cellular & molecular immunology, 2017 - nature.com
Pattern recognition receptors (PRRs) and their signaling pathways have essential roles in
recognizing various components of pathogens as well as damaged cells and triggering …

Think small: zebrafish as a model system of human pathology

JR Goldsmith, C Jobin - BioMed Research International, 2012 - Wiley Online Library
Although human pathologies have mostly been modeled using higher mammal systems
such as mice, the lower vertebrate zebrafish has gained tremendous attention as a model …

Host-pathogen interactions made transparent with the zebrafish model

AH Meijer, HP Spaink - Current drug targets, 2011 - ingentaconnect.com
The zebrafish holds much promise as a high-throughput drug screening model for immune-
related diseases, including inflammatory and infectious diseases and cancer. This is due to …