The in vivo fate of polymeric micelles

Y Cai, J Qi, Y Lu, H He, W Wu - Advanced Drug Delivery Reviews, 2022 - Elsevier
This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

Converging bioprinting and organoids to better recapitulate the tumor microenvironment

X Wang, Y Luo, Y Ma, P Wang, R Yao - Trends in biotechnology, 2024 - cell.com
Bioprinting shows excellent potential for preclinical tumor modeling, with significant
advantages over 2D cell cultures in replicating the tumor microenvironment (TME). Recently …

From 2D to 3D cancer cell models—the enigmas of drug delivery research

I Van Zundert, B Fortuni, S Rocha - Nanomaterials, 2020 - mdpi.com
Over the past decades, research has made impressive breakthroughs towards drug delivery
systems, resulting in a wide range of multifunctional engineered nanoparticles with …

Tumor-on-a-chip model for advancement of anti-cancer nano drug delivery system

C Tian, S Zheng, X Liu, K Kamei - Journal of Nanobiotechnology, 2022 - Springer
Despite explosive growth in the development of nano-drug delivery systems (NDDS)
targeting tumors in the last few decades, clinical translation rates are low owing to the lack of …

In situ biosensing technologies for an organ-on-a-chip

J Kim, J Kim, Y Jin, SW Cho - Biofabrication, 2023 - iopscience.iop.org
The in vitro simulation of organs resolves the accuracy, ethical, and cost challenges
accompanying in vivo experiments. Organoids and organs-on-chips have been developed …

Application of 3D bioprinting in liver diseases

W Li, Z Liu, F Tang, H Jiang, Z Zhou, X Hao, JM Zhang - Micromachines, 2023 - mdpi.com
Liver diseases are the primary reason for morbidity and mortality in the world. Owing to a
shortage of organ donors and postoperative immune rejection, patients routinely suffer from …

Supramolecular Stability of Benzene-1, 3, 5-Tricarboxamide Supramolecular Polymers in Biological Media: Beyond the Stability–Responsiveness Trade-Off

E Fuentes, Y Gabaldón, M Collado… - Journal of the …, 2022 - ACS Publications
Supramolecular assemblies have been gaining attention in recent years in the field of drug
delivery because of their unique formulation possibilities and adaptive behavior. Their non …

Real-time imaging of nanobubble ultrasound contrast agent flow, extravasation, and diffusion through an extracellular matrix using a microfluidic model

MB Cooley, WJ Wulftange, D Wegierak, U Goreke… - Lab on a Chip, 2023 - pubs.rsc.org
Lipid shell-stabilized nanoparticles with a perfluorocarbon gas-core, or nanobubbles, have
recently attracted attention as a new contrast agent for molecular ultrasound imaging and …

Recent advances in vascularized tumor-on-a-chip

CBX Huang, TY Tu - Frontiers in Oncology, 2023 - frontiersin.org
The vasculature plays a critical role in cancer progression and metastasis, representing a
pivotal aspect in the creation of cancer models. In recent years, the emergence of organ-on …

Can supramolecular polymers become another material choice for polymer flooding to enhance oil recovery?

L Sun, Z Zhang, K Leng, B Li, C Feng, X Huo - Polymers, 2022 - mdpi.com
High molecular polymers have been widely studied and applied in the field of enhanced oil
recovery (EOR). At present, the focus of research has been changed to the design of …