Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

In severe COVID-19, the levels of iron (Fe), copper (Cu), zinc (Zn) and selenium (Se), do not
only regulate host immune responses, but modify the viral genome, as well. While low serum …

After more than a year of the COVID‐19 pandemic, SARS‐CoV‐2 infection rates with newer
variants continue to devastate much of the world. Global healthcare systems are …

Ferritin, which includes twenty-four light and heavy chains in varying proportions in different
tissues, is primarily responsible for maintaining the body's iron metabolism. Its normal value …

The progression of SARS-CoV-2 infection has been linked to a hospitalization rate of 20%.
The susceptibility of SARS-CoV-2 infection increases with age, resulting in severe and …

Beside the changes in the gut microbiota in context of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection, the increased use of high-risk broad-spectrum …

Background In the severe forms of COVID-19 and many other infectious diseases, the
patients develop a cytokine storm syndrome (CSS) where pro-inflammatory cytokines such …

The redox reactivity of iron is a double-edged sword for cell functions, being either essential
or harmful depending on metal concentration and location. Deregulation of iron homeostasis …

Background Iron metabolism dysregulation may play a role in organ failure observed in
Coronavirus disease 2019 (COVID-19). This study aimed to explore the whole iron …

Background: Deferoxamine is a potent iron chelator that could remove iron from the virus,
and severe acute respiratory syndrome coronavirus 2 requires iron to replication. Also …