Sugar modified oligonucleotides
PD Cook - US Patent 6,399,754, 2002 - Google Patents
FOREIGN PATENT DOCUMENTS Compositions and methods are provided for the treatment
CA 2017369 11/1990 and diagnosis of diseases amenable to modulation of the DE …
CA 2017369 11/1990 and diagnosis of diseases amenable to modulation of the DE …
Sugar modified oligonucleotides
PD Cook, AM Kawasaki - US Patent 7,138,517, 2006 - Google Patents
Compositions and methods are provided for the treatment and diagnosis of diseases
amenable to modulation of the production of selected proteins. In accordance with pre ferred …
amenable to modulation of the production of selected proteins. In accordance with pre ferred …
Temperature-sensitive plant cells with shunted indole-3-acetic acid conjugation
JH Oetiker, G Aeschbacher - Plant physiology, 1997 - academic.oup.com
Cells of henbane (Hyoscyamus muticus L.) grow indefinitely in culture without exogenous
auxin. Cells of its temperature-sensitive variant XIIB2 grow like the wild type at 26 [deg] C but …
auxin. Cells of its temperature-sensitive variant XIIB2 grow like the wild type at 26 [deg] C but …
Reaction of diazoalkanes with 1-substituted 2, 4-dioxopyrimidines. Formation of O2, N-3 and O4-alkyl products.
JT Kuśmierek, B Singer - Nucleic Acids Research, 1976 - academic.oup.com
In non-aqueous solution, diazomethane and diazoethane react with the O2, O4 and N-3
sites of uridine, thymidine, 1-methyluracil and 1-methylthymine. Diazoethane has a higher …
sites of uridine, thymidine, 1-methyluracil and 1-methylthymine. Diazoethane has a higher …
Process for the preparation of 2'-O-alkyl purine phosphoramidites
PD Cook, DPC McGee, CJ Guinosso - US Patent 6,133,438, 2000 - Google Patents
62 Division of application No. 08/888,880, Jul. 7, 1997, Pat. No. 5.856, 466, which is a
division of application No. 08/410,002, Mar. 23, 1995, Pat. No. 5,646,265, which is a …
division of application No. 08/410,002, Mar. 23, 1995, Pat. No. 5,646,265, which is a …
Synthesis of 2'-O-alkylnucleosides
TS Zatsepin, EA Romanova, SO Tat'yana - Russian chemical reviews, 2002 - pubs.rsc.org
ZACE_ENP 513..534 Page 1 Abstract. The published data on the synthesis of 2H-O-alkylnucleosides
are reviewed. The known methods are systematised and their advantages and disadvantages …
are reviewed. The known methods are systematised and their advantages and disadvantages …
Oligonucleoside linkages containing adjacent nitrogen atoms
YS Sanghvi, PD Cook - US Patent 6,214,551, 2001 - Google Patents
CA (US) 0 287 313 B1 4/1988 (EP). O378 518 1/1990 (EP).(*) Notice: Subject to any
disclaimer, the term of this O 417 999? 9/1990 (EP). patent is extended or adjusted under 35 …
disclaimer, the term of this O 417 999? 9/1990 (EP). patent is extended or adjusted under 35 …
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
PD Cook, YS Sanghvi - US Patent 6,025,482, 2000 - Google Patents
US6025482A - Backbone modified oligonucleotide analogs and preparation thereof
through reductive coupling - Google Patents US6025482A - Backbone modified …
through reductive coupling - Google Patents US6025482A - Backbone modified …
[PDF][PDF] Разработка синтетических подходов к созданию гибридных молекул с цитостатическими свойствами
АА Моисеева, БВ Кузьмич - VIII Молодежная конференция ИОХ РАН, 2021 - ineos.ac.ru
Актуальность работы. Даунорубицин и другие антрациклиновые антибиотики,
выделенные в 60-е годы XX века из Streptomyces peucetius, в настоящее время в …
выделенные в 60-е годы XX века из Streptomyces peucetius, в настоящее время в …
Diazomethane-catalyzed Transesterification of Oxalic Acid Esters
JC Young - Canadian Journal of Chemistry, 1975 - cdnsciencepub.com
En présence d'un alcool, les esters de l'acide oxalique subissent des transestérifications
catalysées par le diazométhane. Dans des conditions douces de réaction, les esters des …
catalysées par le diazométhane. Dans des conditions douces de réaction, les esters des …