Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …

The presence of barriers, such as the blood–brain barrier (BBB) and brain–tumor barrier
(BTB), limits the penetration of antineoplastic drugs into the brain, resulting in poor response …

MR-guided focused ultrasound (MRgFUS) is an emerging technology that can accurately
and transiently permeabilize the blood-brain barrier (BBB) for targeted drug delivery to the …

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, and it is
associated with poor prognosis. Its characteristics of being highly invasive and undergoing …

Diagnostics of cerebrovascular structures and microscopic tumors with intact blood–brain
barrier (BBB) significantly contributes to timely treatment of patients bearing neurological …

The greatest obstacle to using drugs to treat brain tumors is the blood‐brain barrier (BBB),
making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely …

Simple Summary Glioblastoma multiforme (GBM) are among the most lethal tumors. The
highly invasive nature and presence of GBM stem cells, as well as the blood brain barrier …

Background: Microbubbles are widely used as highly effective contrast agents to improve
the diagnostic capability of ultrasound imaging. Mounting evidence suggests that ultrasound …

The blood-brain barrier, while fundamental in maintaining homeostasis in the central
nervous system, is a bottleneck to achieving efficacy for numerous therapeutics. Improved …

The presence of blood–brain barrier (BBB) and/or blood–brain–tumor barriers (BBTB) is one
of the main obstacles to effectively deliver therapeutics to our central nervous system (CNS); …