Impacts of turmeric and its principal bioactive curcumin on human health: Pharmaceutical, medicinal, and food applications: A comprehensive review

MT El-Saadony, T Yang, SA Korma, M Sitohy… - Frontiers in …, 2023 - frontiersin.org
The yellow polyphenolic pigment known as curcumin, originating from the rhizome of the
turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as …

[HTML][HTML] Phenolic metabolites as therapeutic in inflammation and neoplasms: Molecular pathways explaining their efficacy

W Liu, X Cui, Y Zhong, R Ma, B Liu, Y Xia - Pharmacological research, 2023 - Elsevier
Polyphenols, also known as phenolic compounds, are chemical substances containing
aromatic rings as well as at least two hydroxyl groups. Natural phenolic compounds exist …

Tumor-associated macrophages in bladder cancer: biological role, impact on therapeutic response and perspectives for immunotherapy

MM Leblond, H Zdimerova, E Desponds, G Verdeil - Cancers, 2021 - mdpi.com
Simple Summary Tumor-associated macrophages (TAMs) play major roles in solid tumor
development. They can have both anti-tumor and pro-tumor properties depending on their …

Obesity and main urologic cancers: Current systematic evidence, novel biological mechanisms, perspectives and challenges

G Papavasileiou, D Tsilingiris, N Spyrou… - Seminars in Cancer …, 2023 - Elsevier
Urologic cancers (UC) account for 13.1% of all new cancer cases and 7.9% of all cancer-
related deaths. A growing body of evidence has indicated a potential causal link between …

Curcumin in the treatment of urological cancers: Therapeutic targets, challenges and prospects

M Hashemi, S Mirzaei, M Barati, ES Hejazi… - Life sciences, 2022 - Elsevier
Urological cancers include bladder, prostate and renal cancers that can cause death in
males and females. Patients with urological cancers are mainly diagnosed at an advanced …

JAK/STAT of all trades: linking inflammation with cancer development, tumor progression and therapy resistance

HE Sabaawy, BM Ryan, H Khiabanian… - …, 2021 - academic.oup.com
Inflammation is at the forefront of carcinogenesis, tumor progression and resistance to
therapy. The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) …

Targeting mTOR as a cancer therapy: Recent advances in natural bioactive compounds and immunotherapy

A Bouyahya, A El Allam, S Aboulaghras, S Bakrim… - Cancers, 2022 - mdpi.com
The mammalian target of rapamycin (mTOR) is a highly conserved serine/threonine-protein
kinase, which regulates many biological processes related to metabolism, cancer, immune …

A comprehensive review on Ellagic acid in breast cancer treatment: From cellular effects to molecular mechanisms of action

M Golmohammadi, MY Zamanian… - Food Science & …, 2023 - Wiley Online Library
Globally, breast cancer (BC) is the leading cause of cancer‐related deaths in women.
Hence, developing a therapeutic plan to overcome the disease is crucial. Numerous factors …

[HTML][HTML] Curcumin and its novel formulations for the treatment of hepatocellular carcinoma: new trends and future perspectives in cancer therapy

SM Meybodi, P Rezaei, N Faraji… - Journal of Functional …, 2023 - Elsevier
Hepatocellular carcinoma (HCC), as a common malignancy of the liver, is the second
leading cause of cancer-related death in the world and mostly occurs in patients with a …

Herbal Therapies for Cancer Treatment: A Review of Phytotherapeutic Efficacy

A Jenča, DK Mills, H Ghasemi, E Saberian… - … : Targets and Therapy, 2024 - Taylor & Francis
Natural products have proven to be promising anti-cancer agents due to their diverse
chemical structures and bioactivity. This review examines their central role in cancer …