[HTML][HTML] Effects of microbeam radiation therapy on normal and tumoral blood vessels
A Bouchet, R Serduc, JA Laissue, V Djonov - Physica Medica, 2015 - Elsevier
Microbeam radiation therapy (MRT) is a new form of preclinical radiotherapy using quasi-
parallel arrays of synchrotron X-ray microbeams. While the deposition of several hundred …
parallel arrays of synchrotron X-ray microbeams. While the deposition of several hundred …
A matter of space: how the spatial heterogeneity in energy deposition determines the biological outcome of radiation exposure
G Baiocco, S Bartzsch, V Conte, T Friedrich… - Radiation and …, 2022 - Springer
The outcome of the exposure of living organisms to ionizing radiation is determined by the
distribution of the associated energy deposition at different spatial scales. Radiation …
distribution of the associated energy deposition at different spatial scales. Radiation …
A global analysis of viviparity in squamates highlights its prevalence in cold climates
Aim Viviparity has evolved more times in squamates than in any other vertebrate group;
therefore, squamates offer an excellent model system in which to study the patterns, drivers …
therefore, squamates offer an excellent model system in which to study the patterns, drivers …
Preferential effect of synchrotron microbeam radiation therapy on intracerebral 9L gliosarcoma vascular networks
PURPOSE: Synchrotron microbeam radiation therapy (MRT) relies on spatial fractionation of
the incident photon beam into parallel micron-wide beams. Our aim was to analyze the …
the incident photon beam into parallel micron-wide beams. Our aim was to analyze the …
Proton minibeam radiation therapy widens the therapeutic index for high-grade gliomas
Y Prezado, G Jouvion, A Patriarca, C Nauraye… - Scientific reports, 2018 - nature.com
Proton minibeam radiation therapy (pMBRT) is a novel strategy which has already shown a
remarkable reduction in neurotoxicity as to compared with standard proton therapy. Here we …
remarkable reduction in neurotoxicity as to compared with standard proton therapy. Here we …
Toward personalized synchrotron microbeam radiation therapy
Synchrotron facilities produce ultra-high dose rate X-rays that can be used for selective
cancer treatment when combined with micron-sized beams. Synchrotron microbeam …
cancer treatment when combined with micron-sized beams. Synchrotron microbeam …
Tolerance to dose escalation in minibeam radiation therapy applied to normal rat brain: long-term clinical, radiological and histopathological analysis
Y Prezado, P Deman, P Varlet, G Jouvion… - Radiation …, 2015 - meridian.allenpress.com
The major limitation to reaching a curative radiation dose in radioresistant tumors such as
malignant gliomas is the high sensitivity to radiation and subsequent damage of the …
malignant gliomas is the high sensitivity to radiation and subsequent damage of the …
Unexpected benefits of multiport synchrotron microbeam radiation therapy for brain tumors
Simple Summary We unveiled the potential of an innovative irradiation technique that
ablates brain cancer while sparing normal tissues. Spatially fractionating the incident beam …
ablates brain cancer while sparing normal tissues. Spatially fractionating the incident beam …
Increase of lifespan for glioma-bearing rats by using minibeam radiation therapy
Y Prezado, S Sarun, S Gil, P Deman… - Journal of …, 2012 - journals.iucr.org
This feasibility work assesses the therapeutic effectiveness of minibeam radiation therapy, a
new synchrotron radiotherapy technique. In this new approach the irradiation is performed …
new synchrotron radiotherapy technique. In this new approach the irradiation is performed …
Spatially fractionated proton minibeams
Extraordinary normal tissue response to highly spatially fractionated X-ray beams has been
explored for over 25 years. More recently, alternative radiation sources have been …
explored for over 25 years. More recently, alternative radiation sources have been …