With the explosion of gene editing tools in recent years, there has been a much greater
demand for mouse embryo phenotyping, and traditional methods such as histology and …

Application of optical imaging in developmental biology marks an exciting frontier in
biomedical optics. Optical resolution and imaging depth allow for investigation of growing …

Cerebrovascular disease includes all disorders that affect cerebrovascular and cerebral
circulation. Unfortunately, there is currently a lack of a systematic method to image blood …

Several experimental and clinical findings suggest that ethanol consumption during
pregnancy activates an oxidative-inflammatory cascade followed by wide apoptotic …

The embryonic heart is an active and developing organ. Genetic studies in mouse models
have generated great insight into normal heart development and congenital heart defects …

Significance: Prenatal exposure to ethanol causes several morphological and
neurobehavioral deficits. While there are some studies on the effects of ethanol exposure on …

Background The vascular system may be particularly vulnerable to prenatal alcohol
exposure (PAE). Alterations in angiogenesis and epigenetic changes to vascular …

Prenatal ethanol exposure (PEE) can lead to structural and functional abnormalities in fetal
brain. Although neural developmental deficits due to PEE have been recognized, the …

Fetal alcohol spectrum disorders (FASD) describe neurodevelopmental deficits in children
exposed to alcohol in utero. We hypothesized that gestational alcohol significantly alters …

Background Children exposed prenatally to alcohol or cannabinoids individually can exhibit
growth deficits and increased risk for adverse birth outcomes. However, these drugs are …