SARS-CoV-2 Variants and Multisystem Inflammatory Syndrome in Children | New England
Journal of Medicine Skip to main content The New England Journal of Medicine homepage …

Multisystem inflammatory syndrome in children (MIS-C) is defined as a clinically serious
condition requiring hospitalization involving fever, multi-system organ dysfunction, and an …

Multisystem inflammatory syndrome (MIS-C) is a rare condition associated with COVID-19
affecting children, characterized by severe and aberrant systemic inflammation leading to …

Background Although most children and adolescents have had a previous SARS-CoV-2
infection and many continue to receive COVID-19 vaccinations, studies of the effectiveness …

METHODS We included hospitalizations of children with MIS-C and KD from April 2020 to
May 2022 from the Pediatric Health Information System administrative database. Our …

TET2-Driver and NLRC4-Passenger Variants in Adult-Onset Autoinflammation | New England
Journal of Medicine Skip to main content The New England Journal of Medicine homepage …

Background COVID-19 pandemic research efforts have focused on disease phenotypes in
adults. A distinct spectrum of illness has been documented in paediatric populations. We …

The COVID-19 situation in early 2023, more than three years after the start of the pandemic,
has changed significantly. Globally, population-level immunity has increased significantly …

Since the beginning of the pandemic, it's been clear that children are far less at risk of
severe disease from SARS-CoV-2 than adults. Less clear are how it manifests in them and …

Background Paediatric symptomatic SARS-CoV-2 infections associate with two
presentations, acute COVID-19 and paediatric inflammatory multisystem syndrome …