Lung cancer: Biology and treatment options

H Lemjabbar-Alaoui, OUI Hassan, YW Yang… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Lung cancer remains the leading cause of cancer mortality in men and women in the US
and worldwide. About 90% of lung cancer cases are caused by smoking and the use of …

[HTML][HTML] Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment

AC Bibby, S Tsim, N Kanellakis, H Ball… - European …, 2016 - Eur Respiratory Soc
Malignant pleural mesothelioma is an aggressive malignancy of the pleural surface,
predominantly caused by prior asbestos exposure. There is a global epidemic of malignant …

Deep learning-based classification of mesothelioma improves prediction of patient outcome

P Courtiol, C Maussion, M Moarii, E Pronier, S Pilcer… - Nature medicine, 2019 - nature.com
Malignant mesothelioma (MM) is an aggressive cancer primarily diagnosed on the basis of
histological criteria. The 2015 World Health Organization classification subdivides …

Medical and surgical care of patients with mesothelioma and their relatives carrying germline BAP1 mutations

M Carbone, HI Pass, G Ak, HR Alexander Jr… - Journal of Thoracic …, 2022 - Elsevier
The most common malignancies that develop in carriers of BAP1 germline mutations include
diffuse malignant mesothelioma, uveal and cutaneous melanoma, renal cell carcinoma, and …

Crosstalk between DNA damage and inflammation in the multiple steps of carcinogenesis

S Kawanishi, S Ohnishi, N Ma, Y Hiraku… - International journal of …, 2017 - mdpi.com
Inflammation can be induced by chronic infection, inflammatory diseases and
physicochemical factors. Chronic inflammation is estimated to contribute to approximately …

Whole-Exome Sequencing Reveals Frequent Genetic Alterations in BAP1, NF2, CDKN2A, and CUL1 in Malignant Pleural Mesothelioma

G Guo, J Chmielecki, C Goparaju, A Heguy, I Dolgalev… - Cancer research, 2015 - AACR
Malignant pleural mesothelioma (MPM) is an aggressive neoplasm associated with
asbestos exposure. Although previous studies based on candidate gene approaches have …

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for malignant peritoneal mesothelioma: multi-institutional experience

TD Yan, M Deraco, D Baratti, S Kusamura… - Journal of Clinical …, 2009 - ascopubs.org
Purpose This multi-institutional registry study evaluated cytoreductive surgery (CRS)
combined with hyperthermic intraperitoneal chemotherapy (HIPEC) for diffuse malignant …

Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trial

L Calabrò, A Morra, E Fonsatti, O Cutaia… - The Lancet …, 2013 - thelancet.com
Background Monoclonal antibodies to cytotoxic T-lymphocyte antigen 4 (CTLA4) have
therapeutic activity in different tumour types. We aimed to investigate the efficacy, safety, and …

[PDF][PDF] Global mesothelioma deaths reported to the World Health Organization between 1994 and 2008

V Delgermaa, K Takahashi, EK Park… - Bulletin of the World …, 2011 - SciELO Public Health
OBJECTIVE: To carry out a descriptive analysis of mesothelioma deaths reported worldwide
between 1994 and 2008. METHODS: We extracted data on mesothelioma deaths reported …

Molecular pathogenesis of malignant mesothelioma

Y Sekido - Carcinogenesis, 2013 - academic.oup.com
Malignant mesothelioma (MM) is an aggressive tumor arising primarily from the pleural or
peritoneal cavities. It develops by asbestos exposure after a long latency, which is …