Alzheimer's disease and Alzheimer's disease-related dementias in Hispanics: Identifying influential factors and supporting caregivers

P Rawat, U Sehar, J Bisht, AP Reddy… - Ageing Research Reviews, 2024 - Elsevier
Alzheimer's disease (AD) and Alzheimer's disease-related dementias (ADRD) are the
primary public health concerns in the United States and around the globe. AD/ADRD are …

[HTML][HTML] The iceberg of dementia risk: empirical and conceptual arguments in favor of structural interventions for brain health

T Daly - Cerebral Circulation-Cognition and Behavior, 2024 - Elsevier
While pharmacological interventions for dementia struggle to demonstrate improved
outcomes for patients and at-risk populations, non-pharmacological lifestyle interventions …

Frequency of cognitive “super-aging” in three Australian samples using different diagnostic criteria

A Powell, BCP Lam, D Foxe, JCT Close… - International …, 2024 - cambridge.org
Objectives: To investigate the frequency of exceptional cognition (cognitive super-aging) in
Australian older adults using different published definitions, agreement between definitions …

Association of vascular risk factors and cerebrovascular pathology with alzheimer disease pathologic changes in individuals without dementia

L Lorenzini, A Maranzano, S Ingala, LE Collij, M Tranfa… - Neurology, 2024 - neurology.org
Background and Objectives Vascular risk factors (VRFs) and cerebral small vessel disease
(cSVD) are common in patients with Alzheimer disease (AD). It remains unclear whether this …

Association of optic disc pallor and RNFL thickness with cerebral small vessel disease in the PREVENT‐Dementia study

S Gibbon, A Low, C Hamid… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION We tested associations between two retinal measures (optic disc pallor,
peripapillary retinal nerve fiber layer [pRNFL] thickness) and four magnetic resonance …

The PREVENT Dementia programme: Baseline demographic, lifestyle, imaging and cognitive data from a midlife cohort study investigating risk factors for dementia

CW Ritchie, K Bridgeman, S Gregory… - Brain …, 2024 - academic.oup.com
PREVENT is a multi-centre prospective cohort study in the UK and Ireland that aims to
examine midlife risk factors for dementia and identify and describe the earliest indices of …

[HTML][HTML] Cardiovascular risk of dementia is associated with brain–behaviour changes in cognitively healthy, middle-aged individuals

F Deng, ME Dounavi, ERG Plini, K Ritchie… - Neurobiology of …, 2024 - Elsevier
Alzheimer's Disease (AD) neuropathology start decades before clinical manifestations, but
whether risk factors are associated with early cognitive and brain changes in midlife remains …

Neuroimaging and Clinical Findings in Healthy Middle-Aged Adults With Mild Traumatic Brain Injury in the PREVENT Dementia Study

A Low, E McKiernan, MA Prats-Sedano… - JAMA network …, 2024 - jamanetwork.com
Importance Traumatic brain injuries (TBI) represent an important, potentially modifiable risk
factor for dementia. Despite frequently observed vascular imaging changes in individuals …

Associations between sex and lifestyle activities with cognitive reserve in mid-life adults with genetic risk for Alzheimer's disease

Q Qi, F Deng, R Sammon, K Ritchie… - Alzheimer's research & …, 2024 - Springer
Background Females have a higher age-adjusted incidence of Alzheimer's Disease (AD)
than males, even when accounting for longer lifespan and, therefore, stand to benefit the …

Clinical Predictors of Postmortem Amyloid and Nonamyloid Cerebral Small Vessel Disease in Middle-Aged to Older Adults

C Dallaire-Théroux, C Smith… - Neurology: Clinical …, 2024 - AAN Enterprises
Background and Objectives Sporadic cerebral small vessel disease (CSVD) is a class of
important pathologic processes known to affect the aging brain and to contribute to cognitive …