Prefrontal cortex and depression

DA Pizzagalli, AC Roberts - Neuropsychopharmacology, 2022 - nature.com
The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities …

Effect of parental depressive symptoms on offspring's brain structure and function: A systematic review of neuroimaging studies

G Cattarinussi, MH Aarabi, HS Moghaddam… - Neuroscience & …, 2021 - Elsevier
Perinatal Depression (PND) is a severe mental disorder that appears during pregnancy or in
the post-partum. Although PND has been associated with behavioral problems in the …

The Bipolar Illness Onset study: research protocol for the BIO cohort study

LV Kessing, K Munkholm, M Faurholt-Jepsen… - BMJ open, 2017 - bmjopen.bmj.com
Introduction Bipolar disorder is an often disabling mental illness with a lifetime prevalence of
1%–2%, a high risk of recurrence of manic and depressive episodes, a lifelong elevated risk …

Emotion regulating attentional control abnormalities in major depressive disorder: an event-related potential study

B Hu, J Rao, X Li, T Cao, J Li, D Majoe, J Gutknecht - Scientific reports, 2017 - nature.com
Major depressive disorders (MDD) exhibit cognitive dysfunction with respect to attention.
The deficiencies in cognitive control of emotional information are associated with MDD as …

Structural and functional alterations in untreated patients with major depressive disorder and bipolar disorder experiencing first depressive episode: a magnetic …

X Jiang, X Wang, L Jia, T Sun, J Kang, Y Zhou… - Journal of Affective …, 2021 - Elsevier
Background Magnetic resonance imaging (MRI) could assist in identifying objective
biomarkers and follow-up study could effectively improve subjective diagnostic accuracy. By …

'Hot'cognition in major depressive disorder: A systematic review

K W. Miskowiak, A F. Carvalho - CNS & Neurological Disorders …, 2014 - benthamdirect.com
Major depressive disorder (MDD) is associated with significant cognitive dysfunction in both
'hot'(ie emotion-laden) and 'cold'(non-emotional) domains. Here we review evidence …

Neural basis of negativity bias in the perception of ambiguous facial expression

T Ito, K Yokokawa, N Yahata, A Isato, T Suhara… - Scientific reports, 2017 - nature.com
Negativity bias, which describes the tendency to interpret ambiguous stimuli or events as
negative, is often observed in patients with depression and may prevent psychological well …

Negative bias during early attentional engagement in major depressive disorder as examined using a two-stage model: high sensitivity to sad but bluntness to happy …

X Ao, L Mo, Z Wei, W Yu, F Zhou… - Frontiers in Human …, 2020 - frontiersin.org
Negative attentional bias has been well established in depression. However, there is very
limited knowledge about whether this depression-relevant negative bias exits during initial …

Does cognitive dysfunction in bipolar disorder qualify as a diagnostic intermediate phenotype?—a perspective paper

LV Kessing, K Miskowiak - Frontiers in psychiatry, 2018 - frontiersin.org
The present perspective paper addresses and discusses whether cognitive dysfunction in
bipolar disorder qualifies as a diagnostic intermediate phenotype using the Robin and Guze …

Neural correlates of improved executive function following erythropoietin treatment in mood disorders

KW Miskowiak, M Vinberg, L Glerup… - Psychological …, 2016 - cambridge.org
BackgroundCognitive dysfunction in depression and bipolar disorder (BD) is insufficiently
targeted by available treatments. Erythropoietin (EPO) increases neuroplasticity and may …