Mechanisms and functions of intestinal vascular specialization

J Bernier-Latmani, A González-Loyola… - Journal of Experimental …, 2023 - rupress.org
The intestinal vasculature has been studied for the last 100 years, and its essential role in
absorbing and distributing ingested nutrients is well known. Recently, fascinating new …

Genetics of primary sclerosing cholangitis and pathophysiological implications

X Jiang, TH Karlsen - Nature reviews Gastroenterology & hepatology, 2017 - nature.com
Primary sclerosing cholangitis (PSC) is a chronic disease leading to fibrotic scarring of the
intrahepatic and extrahepatic bile ducts, causing considerable morbidity and mortality via …

Exosomal regulation of lymphocyte homing to the gut

EJ Park, O Prajuabjinda, ZY Soe, S Darkwah… - Blood …, 2019 - ashpublications.org
Exosomes secreted from T cells have been shown to affect dendritic cells, cancer cells, and
other T cells. However, little is known about how T-cell exosomes (T exosomes) modulate …

An NKX-COUP-TFII morphogenetic code directs mucosal endothelial addressin expression

TT Dinh, M Xiang, A Rajaraman, Y Wang… - Nature …, 2022 - nature.com
Immunoglobulin family and carbohydrate vascular addressins encoded by Madcam1 and
St6gal1 control lymphocyte homing into intestinal tissues, regulating immunity and …

[HTML][HTML] Nkx2. 3 transcription factor is a key regulator of mucous cell identity in salivary glands

X Gao, T Mukaibo, X Wei, RC Faustoferri, MS Oei… - Developmental …, 2024 - Elsevier
Saliva is vital to oral health, fulfilling multiple functions in the oral cavity. Three pairs of major
salivary glands and hundreds of minor salivary glands contribute to saliva production. The …

Nkx2-3—a slippery slope from development through inflammation toward hematopoietic malignancies

D Vojkovics, Z Kellermayer, B Kajtár… - Biomarker …, 2018 - journals.sagepub.com
The development of peripheral lymphoid tissues from the mesoderm is the result of a
complex convergence combining lymphohematopoietic differentiation with the local …

Quantitative Analysis of NKX2-3 Expression in Human Colon: An Immunohistochemical Study

F Gábris, B Kajtár, Z Kellermayer… - … of Histochemistry & …, 2024 - journals.sagepub.com
In mice, Nkx2-3 homeodomain transcription factor defines the vascular specification of
secondary and tertiary lymphoid tissues of the intestines. In human studies, polymorphisms …

小鼠骨髓间充质干细胞SCA-1+/CD45+/CD31+亚群归巢基因研究

贺继刚, 李洪荣, 桂龙升, 李永武, 严丹, 王平 - 临床心血管病杂志, 2016 - whuhzzs.com
目的: 探讨小鼠骨髓间充质干细胞(mBMSCs) 亚群SCA-1+/CD45+/CD31+ 归巢分子基础. 方法:
以小鼠心脏干细胞表面分化抗原检测mBMSCs 后, 以CD45, CD31 为标准分选得到4 个亚群 …

IL-22–independent protection from colitis in the absence of Nkx2. 3 transcription factor in mice

Z Kellermayer, D Vojkovics, TA Dakah… - The Journal of …, 2019 - journals.aai.org
The transcription factor Nkx2. 3 regulates the vascular specification of Peyer patches in mice
through determining endothelial addressin preference and may function as a susceptibility …

Differential effects of the absence of Nkx2-3 and MAdCAM-1 on the distribution of intestinal type 3 innate lymphoid cells and postnatal SILT formation in mice

D Vojkovics, Z Kellermayer, F Gábris… - Frontiers in …, 2019 - frontiersin.org
Seeding of leukocytes to developing lymphoid tissues in embryonic and early postnatal age
and to the mucosa throughout adulthood depends on the interaction between endothelial …